"Research growing out of practice" best describes the way Dr. James P. McCullough, Jr., Professor of Psychology & Psychiatry of Virginia Commonwealth University, has conducted his 35-year university career. During the mid-1970s, Dr. McCullough began working with chronically depressed outpatients. At the time, chronic depression was considered to be a personality disorder and not thought to be responsive to medication or psychotherapy. Dr. McCullough developed his therapy model, Cognitive Behavioral Analysis System of Psychotherapy (CBASP), while working with chronically depressed patients. He