Lewis was a senior vice president of programming at Air America Radio from 2003-2005. Before that she spent 25 years in the mainstream media, executive producing news and information programs ranging from Real Life with Jane Pauley at NBC, to World News Now with Aaron Brown and Lisa McRee, and Good Morning America at ABC News. At CNN she was executive producer of Greenfield at Large, and American Morning with Paula Zahn. Lewis, a native of Omaha, Nebraska, received her BFA in film and television from NYU.