GEORGE BOX, PHD, DSC, FRS, is R. A. Fisher Professor Emeritus of Statistics and Industrial Engineering at the University of Wisconsin. He has been the director of research for investigators at Imperial Chemical Industries, Princeton University, and University of Wisconsin-Madison. He is a Fellow of the Royal Society of London and the American Academy of Arts and Sciences, and an Honorary Member and Shewhart and Deming Medalist of the American Society for Quality. He was awarded the Samuel S. Wilks Memorial Medal from the American Statistical Association and the Guy Medal in Gold from the Royal...