Veterinary Pharmacology and Toxicology

ISBN-13: 9789400966062 / Angielski / Miękka / 2011 / 838 str.

Y. Ruckebusch; P. -L Toutian; G. D. Koritz

Spis treści

Section I Developmental Pharmacology.- 1 Perinatal pharmacology in ruminant models.- 2 Placental transfer of drugs in ruminant animals.- 3 Drug disposition in the fetus.- 4 Drug disposition in the newborn.- 5 Postnatal development of renal function in goats.- 6 Developmental patterns of penicillin G excretion.- 7 Drug effects during development and carcinogenicity.- 8 Chemical induced teratogenesis.- 9 Levamisole as an immunomodulator in the prevention of neonatal disease.- 10 Development and prophylaxis of anaemia in calves and lambs.- 11 Oral fluid therapy: some concepts on osmolality, electrolytes and energy.- Section II Ruminant Pharmacology.- 12 Drug bioavailability in the developing ruminant.- 13 Oral antibacterial therapy in pre- and postweaning calves.- 14 Influence of ruminant gastrointestinal physiology on the pharmacokinetics of drugs in dosage forms administered orally.- 15 Ruminal influences on drug action.- 16 Recent developments in the treatment of metabolic diseases.- 17 Drug excretion by the mammary gland.- 18 Pharmacology of uterine motility and relaxation.- 19 New prostaglandins: present studies and future.- 20 Worm diseases: economic aspects of anthelmintic treatment.- 21 Pharmacological basis of the treatment of helminth in cattle.- 22 Pharmacokinetics of albendazole, fenbendazole and oxfendazole.- 23 Pharmacokinetics of levamisole in goats and pigs.- 24 The prophylactic activity of imidocarb against tick-transmitted parasitic infections.- Section III Non-Ruminat Pharmacology.- 25 The distribution and function of histamine receptors.- 26 Serotonin and S2 antagonists.- 27 Dopaminergic control of gastro-intestinal motility.- 28 Vomiting and anti-emetics in small animal practice.- 29 Diarrhoea and antidiarrhoeal drugs.- 30 Pharmacology and comparative toxicology of non-steroidal anti-inflammatory agents.- 31 Clinical pharmacokinetic studies of digoxin and digitoxin in the dog.- 32 Influence of anaesthetics and ancillary agents on cardiovascular and respiratory systems in the horse.- 33 Steroidal anti-inflammatory agents in the horse: pharmacokinetics and action on the adrenal gland.- 34 Spasmolytic analgesic drugs and small intestinal function in the horse.- 35 Physiological, pharmacological and therapeutic aspects of some gastrointestinal disorders in the horse.- 36 Pharmacological control of reproductive mechanisms in the equine female.- Section IV Pharmacological Methods.- 37 Clinical utility and limitations of pharmacokinetics.- 38 Pharmacological approach of drugs used in coronary insufficiency and cerebrovascular pathology.- 39 Fever, trace metals and disease. The effect of antipyretic agents.- 40 Efficacy of penicillin against Streptococcus zooepidemicus. Infection model in the horse.- 41 Receptor binding methods: application to the study of cyclo-pyrrolones, a new family of minor tranquillizers.- 42 Multiplicity of kappa opiate sites in the central nervous system.- 43 Hepatocyte cultures as a research tool in pharmacology and toxicology.- 44 Metabolic radical formation from halothane and enflurane and its modification by enzyme induction and inhibition.- 45 Anaesthesia in pharmacological research.- 46 Evaluation of analgesic drug combinations.- 47 Enzyme induction and inhibition.- 48 Rapid induction of cirrhosis in the liver. A model of hepatic disease.- 49 Behavioural analysis of drug action.- 50 Experimental models for respiratory diseases of ruminants and of swine.- Section V Toxicology.- 51 Environmental pollution: the animal as source, indicator and transmitter.- 52 Residues of drugs and pesticides in milk.- 53 Mycotoxin residue problem and human health hazard.- 54 Residues of xenobiotics in animals, milk, and environment in the light of a 13 year surveillance.- 55 Persistence in milk of active antimicrobial intramammary substances.- 56 Evaluation of drug residues in animal tissues.- 57 Photosensitization in ruminants: porphyrins and phylloerythrin.- 58 Fluorosis in the sheep: new data.- 59 Chloramphenicol-propylene glycol toxicity following constant intravenous infusion in horses.- 60 Heavy metal intoxications in horses.- 61 Evaluation of subclinical lead poisoning in dairy cattle.- 62 Poisoning of animals in the Los Angeles area with pesticides (1981).- 63 Toxicological field data in ruminants.- 64 Adverse drug reactions and interaction (1979–81).- Workshop I Medicated Feed.- Workshop II Animal Anaesthesia.