1. An overview of chemical bioregulation in vertebrates 2. Methods to study bioregulation 3. Synthesis, metabolism, and actions of bioregulators 4. Organization of the mammalian hypothalamus-pituitary axes 5. The hypothalamus-pituitary system in nonmammalian vertebrates 6. The hypothalamus-pituitary- thyroid (HPT) axis of mammals 7. The hypothalamus-pituitary- thyroid (HPT) axis of nonmammalian vertebrates 8. The mammalian adrenal glands: cortical and chromaffin cells 9. Comparative aspects of vertebrate adrenals 10. The endocrinology of mammalian reproduction 11. Comparative aspects of vertebrate reproduction 12. Chemical regulation of feeding, digestion, and metabolism 13. Comparative aspects of feeding, digestion, and metabolism 14. Regulation of calcium and phosphate homeostasis in vertebrates 15. Environmental endocrinology of vertebrates Appendix A: Abbreviations Appendix B: Vertebrate phylogeny and evolution Appendix C: Amino acid abbreviations Appendix D: Bioassays Appendix E: Units for measuring hormones Appendix F: Vertebrate tissue types Appendix G: Metabolic pathways