Vasopressin and Oxytocin: Molecular, Cellular, and Clinical Advances

ISBN-13: 9781461372103 / Angielski / Miękka / 2012 / 483 str.

Hans H. Zingg; Charles W. Bourque; Daniel G. Bichet

Opis

This monograph provides a comprehensive overview of recent advances in the field of vasopressin and oxytocin. In the summer of 1997, scientists from over 20 countries congregated in Montreal for the 1997 World Congress of Neurohypophysial Hormones, a conference that united the fields of vasopressin, neurohypophysis and oxytocin in a single joint meeting that gave rise to the present book. The organization of a joint meeting was prompted by several recent developments. Specifically the molecular characterization of the vasopressin/oxytocin receptor family made it mandatory to adopt an integrated view and to discuss the vasopressin/oxytocin ligand/receptor family as a whole. To ensure em- phasis on novelty, the conference focused on advances made over the last two years and also included important contributions by scientists that had not previously been associated with the vasopressin/oxytocin field. Vasopressin and oxytocin are two neurohormones that exert a wide spectrum of cen- tral and peripheral actions. Accordingly, the vasopressin/oxytocin field embraces a large number of different domains, ranging from neuroscience, endocrinology, and oncology to renal, reproductive, and cardiovascular physiology and pathology.

Spis treści

Historical Overview: Vasopressin Receptors: A Historical Survey; S. Jard. Biosynthesis of Vasopressin and Oxytocin. Cell-Specific Gene Expression in Oxytocin and Vasopressin Magnocellular Neurons; H. Gainer. Hypothalamic Transcription Factors and the Regulation of the Hypothalamo-Neurohypophysial System; J.P.H. Burbach, et al. POU Domain Factors in Neural Development; M.D. Schönemann, et al. Local Protein Synthesis in Magnocellular Dendrites: Basic Elements and Their Response to Hyperosmotic Stimuli; Dan Ma, J.F. Morris. Vasopressin Gene Expression in Rat Choroid Plexus; A. Chodobski, et al. Neuronal Activity and Release. Electrophysiological Distinctions between Oxytocin and Vasopressin Neurons in the Supraoptic Nucleus; W.E. Armstrong, J.E. Stern. Mechanisms of Neuroendocrine Cell Excitability; G.I. Hatton, Zhenhui Li. Properties of the Transient K+ Current in Acutely Isolated Supraoptic Neurons from Adult Rat; T.E. Fisher, C.W. Bourque. Gaba b Receptors and Supraoptic Neuronal Activity; Q.J. Pittman, et al. Local Glutamatergic and Gabaergic Synaptic Circuits and Metabotropic Glutamate Receptors in the Hypothalamic Paraventricular and Supraoptic Nuclei; J.G. Tasker, et al. Progesterone Regulates Hypothalamic Oxytocin mRNA Levels through Gamma Aminobutyric Acid; A. Thomas, J.A. Amico. Differential Effects of the Neurosteroid Pregnenolone Sulphate on Oxytocin and Vasopressin Neurones in Vitro; J.B. Wakerley, C.M. Richardson. Regulation of Vasopressin Release by Ionotropic Glutamate Receptor Agonists; D.J. Morsette, et al. Role of N-Methy-D-Aspartate (NMDA) Receptors in Vasopressin and Oxytocin Responses to Emotional Stimuli; K. Yagi, et al. Electrophysiological Studies ofOxytocin Neurons in Organotypic Slice Cultures; P. Jourdain, et al. Inhibitory Actions of Nociceptin (Orphanin FQ) on Rat Supraoptic Nucleus Oxytocin and Vasopressin Neurones in Vitro; N. Doi, et al. New Aspects of Firing Pattern Autocontrol in Oxytocin and Vasopressin Neurones; F. Moos, et al. Intrahypothalamic Vasopressin Release: An Inhibitor of Systemic Vasopressin Secretion? M. Ludwig, G. Leng. Differential Central and Peripheral Release of Vasopressin and Oxytocin in Response to Swim Stress in Rats; M. Engelmann, et al. Pregnancy and Aging: Two Model Systems with Altered Release Patterns of Oxytocin and Vasopressin within the Hypothalamus; I. Neumann, et al. Effect of Age and Testosterone on the Vasopressin Response to Dehydration in F344BNF1 Male Rats; J. Catudioc-Vallero, et al. Evidence for Nitric Oxide (NO) Actions throughout the Forebrain Osmoresponsive Circuit; S.M. Luckman. Gaseous Neurotransmitter Modulation of Vasopressin and Oxytocin Release; M.L. Forsling, A. Grossman. Membrane Excitability in the Neurohypophysis; R.A. Wilke, et al. Effects. Vasopressin's Depolarizing Action on Neonatal Rat Spinal Lateral Horn Neurons May Involve Multiple Conductances; M. Kolaj, L.P. Renaud. Vasopressin Action in the Mammalian Cerebral Cortex; R. Diaz Brinton, et al. Oxytocin, Vasopressin, and the Neuroendocrine Basis of Pair Bond Formation; T.R. Insel, et al. Central Oxytocin Neurotransmission: Receptor Characterisation and Role in Modulating Limbic Circuits in the Peripartum Period; C.D. Ingram, et al. Targeted Reduction of Oxytocin Expression Provides Insights into Its Physiological Roles; W.S. Young III, et al. Phenotypic Expression of and Oxytocin Peptide Null Mutation in Mice; J.T. Winslow, et al. Antiproliferative Effect of Oxytocin through Specific Oxytocin Receptors in H