Vascular Engineering: New Prospects of Vascular Medicine and Biology with a Multidiscipline Approach

ISBN-13: 9784431566359 / Angielski / Miękka / 2018 / 401 str.

Kazuo Tanishita; Kimiko Yamamoto

Spis treści

Chapter 1 Introduction

Chapter 2 Fundamentals of Vascular Bio-fluid and Solid Mechanics

Chapter 3 Fundamentals of Physiology and Biology of Vascular System

Chapter 4 Hemodynamics in Physio- and Pathological Vessels

Chapter 5 Cyclic Stretch-Induced Reorganization of Stress Fibers in Endothelial Cells

Chapter 6 Mechanical Characterization of Vascular Endothelial Cells Exposed to Fluid Shear Stress

Chapter 7 Tensile Properties of Smooth Muscle Cells, Elastin, and Collagen Fibers

Chapter 8 Mechanobiology of Endothelial Cells Related to the Formation of Arterial Disease

Chapter9 Mechanotransduction of Shear Stress by the Endothelium

Chapter 10 Mechanobiology of Endothelial Cells Related to the Pathogenesis of Arterial Disease

Chapter 11 Vascular Engineering of Blood Coagulation

Chapter 12 Vascular Engineering to Make Blood-Compatible Surface

Chapter 13 Vascular Engineering of Circulatory Assist Devices

Chapter 14 Innovations in Measuring Cellular Mechanics

Chapter 15 Innovation of Vascular Engineering by Mechano-medicine

Chapter 16 Integrated Vascular Engineering: Vascularization of Reconstructed Tissue

Chapter 17 Novel Technology to Assay the Multicellular Network: On-Chip Cellomics Technology

O autorze

KazuoTanishita: Waseda University Research Organization for Nano & Life Innovation

Kimiko Yamamoto: Department of Biomedical Engineering, The University of Tokyo

Blurb

This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions — atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction — has generated a focus on developing expertise to both maintain and treat the vascular system. 

As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.