Valproate

ISBN-13: 9783764358365 / Angielski / Twarda / 1999 / 350 str.

Wolfgang Loscher;M. J. Parnham;J. Bruinvels

Opis

In this book, emphasis is placed on the scientific background leading to the discovery of valproate, and its clinical development into one of the most widely used antiepileptic drugs, a milestone in drug therapy. It reviews the state of the drug, and looks at hypotheses on its mechanisms of action, its metabolism into pharmacologically active metabolites, its unique distribution characteristics, and its various clinical uses.