VCD Spectroscopy for Organic Chemists

ISBN-13: 9780367381202 / Angielski / Miękka / 2019 / 370 str.

Philip J. Stephens; Frank J. Devlin; James R. Cheeseman

Opis

Currently, chiral drugs are a major focus of pharmaceutical companies. This book presents the technique of Vibrational Circular Dichroism (VCD) spectroscopy and discusses its applications to the structural characterization of chiral organic molecules. The book provides all of the information about VCD spectroscopy that an organic chemist needs in order to make use of the technique. The authors, experts responsible for much of the existing literature in this field, discuss the experimental measurement of VCD and the theoretical prediction of VCD. They also evaluate the advantages and limitations of the technique in determining molecular structure.

Spis treści

Introduction to Vibrational Circular Dichroism. The Experimental Measurement of Vibrational Absorption and Vibrational Circular Dichroism. The Theory of IR and VCD Spectra. Ab Initio Methods. Conformational Analysis. Analyses of the IR and VCD Spectra of Conformationally Rigid Molecules. Applications of VCD Spectroscopy to Organic Chemistry.

O autorze

Philip John Stephens and Frank J. Devlin are with the University of Southern California in Los Angeles. James R. Cheeseman works with Gaussian, Inc. in Wallingford, Connecticut.