Urinary Tract Infections: Molecular Pathogenesis and Clinical Management

ISBN-13: 9781555817398 / Angielski / Twarda / 2017 / 550 str.

Frederick S. Nolte

Opis

This comprehensive and authoritative volume on infections of the urinary tract covers the range of the field, from molecular pathogenesis to the host response to clinical diagnosis and management. Written for microbiologists, clinical microbiologists, urologists, and pathologists interested in UTIs.

Spis treści

Contributors ixForeword xviiPreface xixI. Clinical Aspects of Urinary Tract Infections1 Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection 3Duane R. Hickling, Tung-Tien Sun, and Xue-Ru Wu2 Clinical Presentations and Epidemiology of Urinary Tract Infections 27Suzanne E. Geerlings3 Diagnosis, Treatment, and Prevention of Urinary Tract Infection 41Paula Pietrucha-Dilanchian and Thomas M. Hooton4 Urinary Tract Infections in Infants and Children 69Theresa A. Schlager5 The Vaginal Microbiota and Urinary Tract Infection 79Ann E. Stapleton6 Asymptomatic Bacteriuria and Bacterial Interference 87Lindsay E. Nicolle7 Bacterial Prostatitis: Bacterial Virulence, Clinical Outcomes, and New Directions 121John N. Krieger and Praveen Thumbikat8 Urosepsis: Overview of the Diagnostic and Treatment Challenges 135Florian M. E. Wagenlehner, Adrian Pilatz, Wolfgang Weidner, and Kurt G. NaberII. Origins and Virulence Mechanisms of Uropathogenic Bacteria9 Reservoirs of Extraintestinal Pathogenic Escherichia coli 161Amee R. Manges and James R. Johnson10 Origin and Dissemination of Antimicrobial Resistance among Uropathogenic Escherichia coli 179Lisa K. Nolan, Ganwu Li, and Catherine M. Logue11 Population Phylogenomics of Extraintestinal Pathogenic Escherichia coli 207Jérôme Tourret and Erick Denamur12 Virulence and Fitness Determinants of Uropathogenic Escherichia coli 235Sargurunathan Subashchandrabose and Harry L. T. Mobley13 Uropathogenic Escherichia coli-Associated Exotoxins 263Rodney A. Welch14 Structure, Function, and Assembly of Adhesive Organelles by Uropathogenic Bacteria 277Peter Chahales and David G. Thanassi15 Pathoadaptive Mutations in Uropathogenic Escherichia coli 331Evgeni Sokurenko16 Invasion of Host Cells and Tissues by Uropathogenic Bacteria 359Adam J. Lewis, Amanda C. Richards, and Matthew A. Mulvey17 Proteus mirabilis and Urinary Tract Infections 383Jessica N. Schaffer and Melanie M. Pearson18 Epidemiology and Virulence of Klebsiella pneumoniae 435Steven Clegg and Caitlin N. Murphy19 Gram-Positive Uropathogens, Polymicrobial Urinary Tract Infection, and the Emerging Microbiota of the Urinary Tract 459Kimberly A. Kline and Amanda L. Lewis20 Integrated Pathophysiology of Pyelonephritis 503Ferdinand X. Choong, Haris Antypas, and Agneta Richter-DahlforsIII. Host Responses to Urinary Tract Infections and Emerging Therapeutics21 Susceptibility to Urinary Tract Infection: Benefits and Hazards of the Antibacterial Host Response 525Ines Ambite, Karoly Nagy, Gabriela Godaly, Manoj Puthia, Björn Wullt, and Catharina Svanborg22 Innate Immune Responses to Bladder Infection 555Byron W. Hayes and Soman N. Abraham23 Host Responses to Urinary Tract Infections and Emerging Therapeutics: Sensation and Pain within the Urinary Tract 565Lori A. Birder and David J. Klumpp24 Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections 589Valerie P. O'Brien, Thomas J. Hannan, Hailyn V. Nielsen, and Scott J. HultgrenIndex 647