Unresolved Problems in Haemophilia

ISBN-13: 9780852003886 / Angielski / Miękka / 1982 / 245 str.

C. D. Forbes; C. D. Forbes

Opis

Lowe vii List of Contributors Professor Charles Abildgaard, Dr. Geijlswijk, Department of Paediatrics, Department of Haematology, 4301 X Street, University Hospital, Sacramento, Utrecht, California 95817 The Netherlands Dr. L.

Spis treści

Section I Liver Disease in Haemophilia.- Opening remarks.- 1 The epidemiology of Factor VIII and IX associated with hepatitis in the UK.- Discussion.- 2 Viruses causing hepatitis.- Discussion.- 3 Clinical, immunological and histological aspects of non-A, non-B hepatitis in haemophiliacs.- Discussion.- 4 Liver biopsy in non-A, non-B hepatitis.- 5 Experience of liver disease in haemophilia.- Discussion.- 6 The development of hepatitis B vaccines and antiviral therapy.- Discussion.- General Discussion.- Section II Therapy for Haemophilia.- Opening remarks.- 7 The cost of care.- Discussion.- 8 The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleedings in patients with haemophilia A with an inhibitor to Factor VIII.- Discussion.- 9 Therapeutic use of DDAVP in haemophilia and von Willebrand’s disease.- Discussion.- 10 Polyelectrolytes and preparation of Factor VIIIC.- Discussion.- 11 Oral administration of Factor VIII in lipid vesicles.- Discussion.- 12 Use of activated prothrombin complex in Factor VIII inhibitors.- Discussion.- 13 Immune complex disease in haemophilia.- Discussion.- Section III Factor VIII — Structure, Function and Genetics.- 14 Factor VIII — structure and function.- Discussion.- 15 Factor VIIIC — immunology and activity.- Discussion.- Additional Discussion of Chapters 14 and 15.- 16 Genetics of Factor VIII.- Discussion.- 17 Prenatal diagnosis of haemophilia A and Christmas disease.- Discussion.- Section IV Orthopaedic Problems.- 18 Joint surgery in haemophilia.- Discussion.