Understanding Radiation Biology: From DNA Damage to Cancer and Radiation Risk

ISBN-13: 9780367255152 / Angielski / Twarda / 2019 / 252 str.

Kenneth Chadwick

Opis

This textbook provides a exploration into the action of radiation, taking readers into the cell and discussing the damage and the consequences of radiation exposure to living matter. This book will provide the foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, and medicine.

Spis treści

PART I: Ionising Radiation Effects. 1. The Molecular Model and DNA Double Strand Breaks. 2. The Molecular Model for Cellular Effects. 3. The Link from Molecular Lesion to Cellular Effects. 4. DNA Double Strand Breaks and Chromosomal Aberrations. 5. The Effect of Dose Rate, Fractionation and Post-Irradiation Repair. 6. Radiation Quality. 7. Radiation-Induced Cancer. 8. Radiation-Induced Lethality. 9 Radiological Protection. PART II: Ultraviolet Light Effects. 10. The Molecular Model for the Cytotoxic Action of UV Light. PART III: Genotoxicology. 11. An Assessment of the Risk of Chemical Mutagens.

O autorze

Dr. K. H. Chadwick, now retired, worked as a research scientist in the Netherlands before moving to Belgium to manage research contracts on radiation biological effects in the Euratom Radiation Protection Research Programme of the European Commission in Brussels. He also served on the editorial board of the Journal for Radiological Protection for 10 years and is a fellow of the Institute of Physics (FInst P) and the Society for Radiological Protection (FSRP).