Brian Hooton became a Research Fellow in the Nuclear Physics Division at Harwell in 1961. In 1968 he had a sabbatical year at Chalk River, the Atomic Energy of Canada. Upon his return to Harwell, he became a Group Leader. In 1983 he was appointed as the Senior Advisor to the Secretary (SAS) at the London HQ of the UKAEA, where he had very broad responsibilities across the whole of the UKEAE's sites. Hooton retired from the UKAEA in 1991 and set up Nuclear Consultancy Services Ltd offering consultancy services to the nuclear industry.