Ultrasound Contrast Agents: Targeting and Processing Methods for Theranostics

ISBN-13: 9788847014930 / Angielski / Miękka / 2009 / 200 str.

Paradossi, Gaio

Opis

The book provides a highlight of the state of art in the research of novel ultrasound contrast agents (UCAs). Main progresses on the multifunctional aspects of next-generation UCAs concern targeting and drug release properties, perfusion and biointerface behaviour, ultrasound scattering performance, signal processing, electronic equipment.

Recenzje

From the reviews: "Leading experts in this field present the latest research and knowledge within 13 chapters from the development of new echogenic injectable agents and devices to interactions with cells and tissues including the development of hard- and software for detecting and evaluating contrast agents - many prominent up-to-date items are covered by this book. ... The book is dedicated to leaders with a background in theory who want to deepen their knowledge with up-to-date research results and are interested in ultrasound contrast agents' future applications." (Christian Kollmann, Ultraschall in der Medizin, Vol. 31, June, 2010)

Spis treści

Towards Ultrasound Molecular Imaging.- Use of Microbubbles as Ultrasound Contrast Agents for Molecular Imaging.- Design of Novel Polymer Shelled Ultrasound Contrast Agents: Towards an Ultrasound Triggered Drug Delivery.- Lipidic Microbubble Targeting of Surface Proteins Using an in Vitro System.- Protein Interactions with Microballoons: Consequences for Biocompatibility and Application as Contrast Agents.- Polymer Based Biointerfaces: A Case Study on Devices for Theranostics and Tissue Engineering.- Ultrasound Contrast Agent Microbubble Dynamics.- Characterization of Acoustic Properties of PVA-Shelled Ultrasound Contrast Agents.- Novel Characterization Techniques of Microballoons.- A Comparative Analysis of Contrast Enhanced Ultrasound Imaging Techniques.- Remote Measurement of the Ultrasound Contrast Agent Concentration.- Bubble Behavior Testing (BBT) System for Ultrasound Contrast Agent Characterization.- A New Flexible Ultrasound Scanner Suitable for Research Topics.

Blurb

Recent advancements in nano/micro materials and related characterization approaches allow the design of a new type of ultrasound contrast agents (UCAs) with enhanced multifunctional behaviour. This is chance is also supported by the recent achievements in modelling and signal processing.

This book provides the state of art of the research activity of two successful European projects, TAMIRUT and SIGHT, addressing an integrated system, encompassing the contrast agent, the hardware equipment and the processing strategies, as a key tool for a combined diagnostic and therapeutic approaches (theranostics) in medical ultrasound.