Twin and Family Studies of Epigenetics, 29

ISBN-13: 9780128209516 / Angielski / Miękka / 2021

Shuai Li; John Hopper; Trygve Tollefsbol

Spis treści

ART 1 Introduction 1. Value of twin and family study designs for epigenetic research 2. Evaluation and measurement of epigenetic modifications in population-based studies

PART 2 Human health applications 3. Discordant monozygotic twin studies of epigenetic mechanisms in mental health 4. DNA methylation and breast cancer risk: value of twin and family studies 5. Twin and family studies on epigenetics and oral health 6. Twin and family epigenetic studies of type 2 diabetes 7. Twin and family studies on epigenetics and obesity 8. DNA methylation and blood pressure in Chinese adult twins 9. Twin and family studies on epigenetics of autoimmune diseases 10. Twin studies on the epigenetics of selected neurological disorders and carotid artery disease 11. Disease-discordant twin studies of epigenetics and cancer 12. Sex differences in epigenetic profiles: The value of twin studies

PART 3 Emerging approach 13. Combining twin-family designs with measured genetic variants to study the causes of epigenetic variation 14. Imaging epigenetics and the radiogenomics 15. DNA methylation changes specific to environmental exposures: The strengths of twin studies using cigarette smoking as an example 16. Time trends in epigenetic signatures and population health risks 17. Ambient air pollution and human epigenetic modifications