Twentieth Century Mouse Genetics: A Historical and Scientific Review

ISBN-13: 9780128240168 / Angielski / Miękka / 2021 / 344 str.

Robert P. Erickson

Recenzje

"This book will have strong appeal to a limited audience. Those interested in the history and development of mouse genetics, and of mouse genetics in the wider context of the history of genetics, will find this book an interesting read. Indeed, it stands out from other books covering similar topics by the personal experience of the author in the field. " --© Doody's Review Service, 2021, Mark F. Sanders, PhD, reviewer, expert opinion

Spis treści

1. The origins of mouse genetics and the discovery of the T-locus
2. The evolutionary modern synthesis, t-haplotypes in the wild, and reproductive isolation
3. Linkage studies, cytogenetics, and the discovery that t-haplotypes consist of a series of inversions-an over-the-Century Project
4. Developmental genetics and recessive t-lethals
5. More population genetics with particular attention to the effects of t-allele mediated transmission ratio distortion
6. Mutation studies including those targeting the T/t-complex-a century long project
7. Immunogenetics and the failed search for t-antigens-from mid-century and continuing to it's end
8. Gametogenesis and the genetics of gametes, including t-haplotype segregation distortion
9. The cloning era and the cloning of Brachury and other T/t complex genes
10. X-inactivation, epigenetics, and imprinting, including of the T/t complex
11. Sex determination, sex differentiation, and the Y chromosome-a mostly last quarter of the century effort
12. Pharmacogenetics-a mostly last half of the century effort
Book Bibliography