Tumors of the Central Nervous System, Volume 10: Pineal, Pituitary, and Spinal Tumors

ISBN-13: 9789402400991 / Angielski / Miękka / 2016 / 364 str.

M. A. Hayat

Opis

This volume features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery.

Recenzje

From the reviews:

"This is an outstanding book on every molecular mediator of cancer stem cells, angiogenesis, surface markers, and CAD mediators of oncogenesis in the brain. ... This is a very good book for neuropathologists and neurosurgeons. ... I have no reservations about recommending this book for scholars interested in the field." (Joseph J. Grenier, Amazon.com, June, 2014)

Spis treści

Preface I. Pineal tumors 1. Papillary tumor of the pineal region 2. Pineal region tumors: clinical aspects 3. Papillary tumor of the pineal region: diagnosis 4. Pineal parenchymal tumors: immunohhistochemistry 5. Pineal parenchymal tumors: diagnostics and prognosis 6. Papillary tumors of the pineal region: diagnosis and treatment 7. Pineal region tumors: optimal neurosurgical treatment II. Pituitary tumors 8. Pituitary tumors: genetics and heritable predisposition 9. Xanthogranulomas associated with pituitary adenomas: magnetic resonance imaging 10. Pituitary adenoma and craniopharyngioma: an overview 11. Familial pituitary adenomas: an overview 12. Papillary glioneuronal tumor 13. Solitary fibrous tumor 14. Pituitary adenomas: mcm2 protein as a cell proliferation marker 15. Pituitary adenomas: role of cyclin-dependent kinase inhibitors 16. Pituitary tumorigenesis: role of regulation of wee1 kinase by micrornas 17. Pituitary tumor cells: role of pkcα, pkcδ, and pckɛ expression 18. Pituitary adenoma: role of hmga proteins 19. Pituitary adenomas: role of e-cadherin in tumor invasion 20. Pituitary tumorigenesis: role of the wnt signaling pathway 21. The role of aryl hydrocarbon receptor (ahr) and ahr-interacting Protein (aip) in the pathogenesis of pituitary adenomas 22. Pituitary tumors: role of pituitary tumor- transforming gene-1 (pttg1) 23. Pituitary adenomas: endoscopic endonasal transphenoidal Technique 24. Pituitary adenoma patients: hypofractionated cyberknife Radiosurgery (method) 25. Transspheniodal/transcranial surgery of pituitary adenomas: Prognosis-related occurrence for the trigemino-cardiac reflex III. Spinal tumors 26. Spinal extradural meningiomas 27. Spinal cord ganglioglioma 28. Spinal angiolipoma: diagnosis and treatment 29. Spinal cord injury: tissue engineering using neural stem cells 30. Pediatric spinal tumors: total removal using laminotomy 31. Treatment of metastatic spinal epidural disease: surgery versus radiotherapy 32. Metastatic spinal cord compression from synovial sarcoma: surgical resection 33. Adult spinal intramedullary ependymomas: complete resection 34. Spinal intramedullary astrocytomas: prognostic factors Index.

Blurb

Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research—the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research.

 

The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.