Tumor Therapy Monitoring with Diffuse Optical Spectroscopies : Preclinical and Clinical Applications

ISBN-13: 9783639089042 / Angielski / Miękka / 2009 / 136 str.

Ulas Sunar

Opis

The diffuse optical technique using Near-Infrared (NIR) light provides a promisingmeans for non-invasive imaging and clinical diagnosis of deep tissues. This book focuses on a multi-modal diffuse optical technique combining two qualitatively different methodologies: Diffuse Reflectance Spectroscopy (DRS) and Diffuse Correlation Spectroscopy (DCS). This approach permits real-time, non-invasive and simultaneous quantification of tissue hemoglobin concentration, blood oxygen saturation and blood flow. This book outlines the basic principles, mathematical modeling and then practical instrumentation that enable monitoring of tumor responses to therapies in preclinical and clinical contexts. Targeted audience of this book is scientists who are interested in basic principles of diffuse optics and its applications to translational research and medical doctors who are interested in practical tools for therapy monitoring in clinics.

O autorze

Dr. Ulas Sunar earned his Ph.D. in Physics from University of
Pennsylvania, Philadelphia in 2006. He worked as a postdoctoral
scholar in Department of Radiology at University of California
San Diego. He has been with Roswell Park Cancer Institute, PDT
Center, as Assistant Professor since November 2007.