Trends in Stem Cell Proliferation and Cancer Research

ISBN-13: 9789400762107 / Angielski / Twarda / 2013 / 661 str.

Rodrigo Resende; Henning Ulrich

Opis

The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.

Spis treści

PART I   Molecular Bases for Stem and Cancer Cells Proliferation

    1      An introduction to proliferation and migration of stem cells
            and cancer
Micheli Mainardi Pillat, Talita Glaser, Telma Tiemi Schwindt and Henning Ulrich

    2      The role of cell adhesions, cell junctions and extracellular
            matrix in normal development and carcinogenesis
Anderson K. Santos, Fernanda M. P. Tonelli, Daniel A. F. Silva, Kátia N. Gomes, Luiz O. Ladeira and Rodrigo R. Resende 

    3      The embryonic rest hypothesis of cancer development:150
            years later
Mariusz Z. Ratajczak, Maciej Tarnowski, Sylwia Borkowska, Karol Serwin. 

 4        Are calcium channels more important than calcium influx for cell proliferation ?
Anne-Sophie Borowiec, Gabriel Bidaux and Thierry Capiod 

⁵          Role of calcium signaling in stem cells and cancer cells
         proliferation
Maria Jimena Amaya, Vânia A. M. Goulart, Anderson K. Santos, Alexandre H. Kihara, Silvia Guatimosim, Rodrigo R. Resende. 

6        Formation and function of lipid droplets in inflammation
          and cancer
João P.B. Viola, André L.S. Cruz, Miriam B.F. Werneck, Patricia T. Bozza 

7        The role of sphingolipids in modulating pluripotency of stem
          cells
Salman B. Hosain, Ronald A. Hill, Yong-Yu Liu 

PART II  Signaling Pathways to Cancer Cells Fate  

8        Signaling pathways of cbl-b and its role on peripheral t cell
          tolerance
K Venuprasad  

9        BH3-only proteins in cancer and apoptosis
Fabio Ghiotto, Claudya Tenca, Franco Fais and Silvia Bruno 

10    Signaling pathways of mta family proteins as regulators of
        cancer progression and metastasis
Yasushi Toh, Garth L. Nicolson 

11    Signalling pathways of β-catenin/jnk on carcinogenesis
Eliana Kalakouti, Roya Babaei-Jadidi and Abdolrahman S. Nateri 

12    The regulation of the jnk cascade and programmed cell death by
        nf-κb: mechanisms and functions
Jason Bennett, Marta Moretti, Anil K. Thotakura, Laura Tornatore and Guido Franzoso 

PART III  Uncontrolled Physiology Process Guiding to Cancer Cells 

13    Migration, metastasis and more: the role of chemokines in the
        proliferation, spreading and metastasis of tumors
Rolf Mentlein, Kirsten Hattermann and Janka Held-Feindt 

14    Autophagy, cell death, and cancer
Maryam Mehrpour, Ahmed Hamaï and Patrice Codogno 

15    The duality of stem cells – double edged sword in tumour
        evolution and treatment
Urška Tajnšek, Helena Motaln, Nataša Levičar^, Ana Rotter and Tamara T.Lah 

16    Glioblastoma stem cells and implications for chemoresistance
Suzana A. Kahn, Ema Torrado, Dora Brites, Vivaldo Moura Neto 

17    The tumor microenvironment as a transient niche: a modulator of
        epigenetic states and stem cell functions
Lorena E. Mora-Blanco, James B. Lorens, and Mark A. LaBarge 

18    Tumor-associated neutrophils (tans)
André Gustavo Oliveira, Rodrigo Guabiraba, Mauro Martins Teixeira and Gustavo Batista Menezes 

19    MicroRNA control of apoptotic programs in cancer
Reena V. Kartha and Subbaya Subramanian 

PART IV  Therapeutic Strategies for Anticancer Treatment 

20    Markers of cancer stem cells and their functions
Olivier Gires  

21    Cancer cell dormancy: potential therapeutic targets to eradicate
        cancer cells within the niche
Jessian L.Munoz, Jacqueline M. Park, Sarah A. Bliss, Pranela Rameshwar 

22    Modulating apoptosis in cancer therapy with ultrasound and high
        intensity nanosecond electric pulses
Tinghe Yu, Minghe Wu, Ping Huang, Lina Hu 

23    Targeting cell cycle for anticancer treatment and neuroprotection Yun Dai, Shuang Chen, Liang Yi, Minhui Xu