Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment

ISBN-13: 9780857299192 / Angielski / Twarda / 2011 / 266 str.

David Abraham;Clive Handler;Michael Dashwood

Opis

Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based. Newly qualified and trained physicians are working in multidisciplinary groups of cardiologists, vascular surgeons, cardiac surgeons, lipidologists, diabetologists. Clinicians in the US, Australasia, the Far East and western Europe are interested in the molecular basis and treatments of vascular medicine and this encompasses translational medicine. This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Spis treści

Preface
Foreword
Section 1: Vascular Biology
1. The Biology of Endothelin
2. Endogenous inhibitors of NO synthesis
3. Pericytes: Adaptable vascular progenitors
4. Free radicals and oxidant stress

Section 2: Complications and Treatments in Human Vascular Disease
5. Genomics and cardiovascular disease 
6. Surgical trauma and graft performance in patients undergoing coronary artery bypass surgery    

Section 3: Clinical and Basic Aspects of Vascular Medicine
7. Pulmonary Arterial Hypertension
8. Inflammation in pulmonary arterial hypertension
9. Cell therapy for cardiovascular disease
10. Clinical applications of CV Imaging
11. Cardiovascular disease in women

Session 4: Surgical intervention for Vascular Complications
12. Non-pharmacological treatment of peripheral vascular disease
13. Surgical approaches to aneurysm repair
14. Delivering improving treatment for cardiovascular disease

O autorze

Dr Clive Handler BSc, MD, MRCP,FACC, FESC is an Honorary Consultant in the National Pulmonary Hypertension Unit at The Royal Free Hospital, London and Consultant Cardiologist at Highgate Hospital, London. He was previously Consultant Cardiologist at Northwick Park and St Mary's Hospitals, London. He trained at Guy's Hospital Medical School and at St Luke's Hospital Milwaukee, University of Wisconsin. Dr Gerry Coghlan MD, FRCP is Consultant Cardiologist and Director of the National Pulmonary Hypertension Unit at the Royal Free Hospital. He trained in Dublin and at Harefield and the Royal Free Hospitals. He is an international authority on Pulmonary Hypertension but has wide interests in all aspects of the management of coronary heart disease and angioplasty. He has written several books with Dr Clive Handler as well as scientific papers on pulmonary hypertension and other aspects of cardiology.

Blurb

Modern medicine is increasingly focused on integrating the results of basic scientific research and clinical research, “translational medicine” to provide improved patient care. This collaborative approach which is a “two way street” has proven very useful in various fields in cardiovascular medicine.  

 

Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment provides extensive information on new and exciting advances in such topics as surgery and non-pharmacological treatments for atherosclerotic disease of the aorta, pulmonary arterial hypertension, cytoprotective mechanisms in the vasculature, and the “Broken Heart Syndrome”. The Editors and their expert panel of contributors have explored the bi-directional and integrated approaches of translational cardiovascular medicine, linking basic science to patient care.

 

This book is a highly useful method to understand these complex topics and provides considerable insight into important areas of translational cardiovascular medicine and key bibliographies for the reader.