Transgenic Plants: A Production System for Industrial and Pharmaceutical Proteins

ISBN-13: 9780471964438 / Angielski / Twarda / 1997 / 364 str.

Meran R. Owen; Meran R. Cwen; J. Pen

Opis

Transgenic Plants: A Production System for Industrial and Pharmaceutical Proteins provides a detailed guide to the principles and practice of using transgenic plants as a system for the production of heterologous proteins. It is unique in that it covers the complete process of heterologous protein production in plants, from the initial transformation of the plant, through to transcription, transgene stability and finally the downstreaming processing events for protein purification. Written by an international team of industrialists and academics, this book describes:
* the fundamental issues associated with expressing heterologous proteins in plants;
* a number of detailed examples of the successful small-and large-scale production of proteins;
* the essentials of patenting; and
* the commercial exploitation.
Transgenic Plants: A Production System for Industrial and Pharmaceutical Proteins will be of interest to plant biotechnologists, molecular biologists and protein biochemists in the biotechnology and pharmaceutical industries.

Spis treści

Partial table of contents:

FUNDAMENTAL ASPECTS IN THE PRODUCTION OF RECOMBINANT PROTEINS IN PLANTS.

Expression in Plants.

The Production of Recombinant Glycoproteins with Defined Non–Immunogenic Glycans.

Downstream Processing of Proteins from Transgenic Plants.

Comparison of Host Systems for the Production of Recombinant Proteins.

Transgene Stability.

EXAMPLES.

Industrial Enzymes.

Pharmaceutical Proteins.

COMMERCIALIZATION.

Patents and Biotechnology.

Commercialization of Phytase–Containing Seed.

Index.