Transdermal Fentanyl: A New Approach to Prolonged Pain Control

ISBN-13: 9783540544401 / Angielski / Miękka / 1991 / 203 str.

Klaus A. Lehmann; Detlev Zech

Opis

An examination of a new administration mode for the management of pain, which explores such topics as the physiology of transdermal permeation, the present state of acute and chronic pain management and clinical studies with special emphasis on analgesic efficacy and side effects.

Spis treści

I Transdermal Therapeutic Systems — An Introduction.- Transdermal Permeation: Physiological and Physicochemical Aspects.- Transdermal Therapeutic Systems in Clinical Use: Development and Applications.- II Current Aspects of Pain Management.- Postoperative Pain.- Cancer Pain.- Pain Management and Quality of Life in Cancer Patients.- Opioid Analgesia for Chronic, Nonmalignant Pain.- III Noninvasive Fentanyl Application.- Pharmacokinetics of Fentanyl.- Premedication and Pain Management with Oral Transmucosal Fentanyl.- Transdermal Fentanyl: an Overview of Pharmacokinetics, Efficacy and Safety.- IV Postoperative Pain Management with TTS Fentanyl.- Pharmacokinetics and Pharmacodynamics.- Clinical Experience.- Respiratory Safety.- TTS Fentanyl in Combination with Patient-Controlled Analgesia.- V Cancer Pain Management with TTS Fentanyl.- Clinical Experience.- VI Other Transdermal Therapeutic Systems for Anesthesia and Pain Management.- Local Anesthetics: Eutectic Mixture of Local Anesthetics.- Scopolamine.