Total Exposure Health: An Introduction

ISBN-13: 9780367505417 / Angielski / Miękka / 2022 / 329 str.

Kirk A. Phillips;Dirk P. Yamamoto;Leeann Racz

Opis

This book provides a comprehensive overview of the concept of "Total Exposure Health" and presents details on subject areas which make up the framework. It provides in-depth coverage of the science and technology supporting exposure and risk assessment. This includes advances in toxicology and the "-omics" as well as new techniques for exposure assessment. The book concludes with a discussion on bioethics implications, including ethical considerations related to genetic testing. Discusses advances in exposure monitoring Presents a systems biology approach to human exposures Examines how overall well-being translates to worker productivity Considers the link between work-related risk factors and health conditions Covers the study of genomics in precision medicine and exposure science Explores bioethics in genomic studies Aimed at the exposure professionals (industrial hygienists, toxicologists, public health, environmental engineers), geneticists, molecular biologists, engineers and managers in the health and safety industry as well as professionals in the public administration field.

Spis treści

Section I: Overview and Fundamentals 1. Total Exposure Health: An Exposure Science Framework for the Fourth Industrial Age 2. The Individual Exposure Health Risk Profile (IEHRP)—Developing a Risk Profile Tool beyond Dose Response 3. In Pursuit of Total Exposure Health: Leveraging Exposure Science, the Omics, and Other Emerging Technologies 4. Total Worker Health^®: Bridging Worker Exposure and Well-Being 5. Industrial Hygiene: A Foundational Role in Total Exposure Health Section II: Advances in Toxicology and the -Omics 6. Personalizing Environmental Health for the Military—Striving for Precision 7. In Silico Identification of Protein Targets for Chemical Neurotoxins Using ToxCast In Vitro Data and Read-Across within the QSAR Toolbox 8. "Omics": An Introduction 9. Silicone Wristbands and Wearables to Assess Chemical Exposures 10. Total Exposure Hearing Health Preservation 11. The Role of Noise Exposure as an Element of Total Exposure Health: Determination of 24-Hour Noise Exposure Profiles on U.S. Navy Aircraft Carriers 12. Identifying Exposures and Health Outcomes in Former Worker Populations 13. Personal Environmental Exposure Sensors and the Internet of Things 14. Sensor Platforms and Wireless Networks 15. Data Integration and Services 16. Exposure Health Informatics Ecosystem Section III: Bioethics 17. Bioethics and Precision Medicine: Focus on Information Technology 18. Unresolved Ethical Questions Raised by Genomic Sequencing Research 19. Genomics, Big Data, and Broad Consent: A New Ethics Frontier for Prevention Science