Tolnaftate loaded nanofibers for regimen of dermatophytosis

ISBN-13: 9786202077026 / Angielski / Miękka / 2017 / 68 str.

Shashi Kiran Misra; Himanshu Pandey; Sandip Patil

Opis

This book offers a comprehensive introduction on dermatophytosis, its etiology and causative agents. Here we described nanotechnology based novel topical drug delivery system for successful regimen of dermatophytosis. It is a kind of topical fungal infection, the most common cause of skin bug in the world, generally underestimated and ignored. It is commonly caused by immensely mortifying and keratinophilic fungal eukaryotes which invade keratinized tissues and generate different tinea diseases in Mediterranean countries. We herein fabricated nanofibers/ scaffolds embedded with thiocarbamate derivative topical antifungal tolnaftate first time to target complete elimination of dermatophyte at site of infection. In this regard, biocompatible Eudragit grades (ERL100 and ERS100) were selected to provide better adhesion on site of dermatophytosis, ample absorption of exudates during treatment and also customizing controlled drug release.

O autorze

Shashi Kiran Misra - Assistant professor at Institute of Pharmacy, C.S.J.M.University, Kanpur, Uttar Pradesh, India. Working on projects of electrospunned antimicrobial nanofibers and dressing materials, their evaluation and suitability for tissue engineering and skin regeneration.