List of Illustrations viiiAcknowledgments xixForeword xxiiiPreface xxvAbout the Authors xxxiCHAPTER 1 Fear or Terror on Every Countenance: Yellow Fever 1CHAPTER 2 Of Mice and Men: Animal Models of Viral Infection 19CHAPTER 3 Filling the Churchyard with Corpses: Smallpox and the Immune Response 43CHAPTER 4 What Can Be Seen: From Viral Inclusion Bodies to Electron Microscopy 65CHAPTER 5 The Turning Point: Cytopathic Effect in Tissue Culture 93CHAPTER 6 A Torrent of Viral Isolates: The Early Years of Diagnostic Virology 129CHAPTER 7 Imaging Viruses and Tagging Their Antigens 165CHAPTER 8 Immunological Memory: Ingenuity and Serendipity 209CHAPTER 9 To the Barricades: The Molecular Revolution 245CHAPTER 10 The World Changed: The COVID-19 Pandemic 285APPENDIX Chapter timelines 349GLOSSARY 361Index 369