Tissue Type Plasminogen Activity: Volume II

ISBN-13: 9781315898223 / Angielski / Twarda / 2017 / 187 str.

Cornelius Kluft

Opis

This book is made possible by the enthusiastic contributions of the authors of the chapters. They have been invited from young and active scientists in the field of t-PA research. I am grateful for their contribution and for the fact that all accepted the specifications of their chapter in order to obtain a structured book. Inevitably, some overlap does exist; on the one hand to enable controversial or unsettled areas to be discussed by the different experts with a different approach and background.It is a particular pleasure and honor that Dr. T. Astrup, as an eye-witness and essential contributor to the history of t-PA discovery and research, gives a unique account of the history of t-PA research in the first chapter of the book.

Spis treści

Section 3: Physiology 11. Synthesis and Secretion Plasminogen Activators and Plasminogen Activator Inhibitor by Endothelial Cells 12. Mechanisms Involved in Short-Term Changes in Blood Levels of t-PA 13. Turnover and Clearance of t-PA 14. Regulation of the Plasminogen Activator Level in Blood, Section 4: Aspects 15. Biological Variations in t-PA Activity and Antigen 16. Clinical Relevance of t-PA Levels and Fibrinolytic Assays 17. Thrombolytic Therapy with t-PA 18. Stimulation of Endrogenous Fibrinolysis

O autorze

Kluft, Cornelius