Thyroid Cancer : From Emergent Biotechnologies to Clinical Practice Guidelines

ISBN-13: 9781439862216 / Angielski / Twarda / 2011 / 408 str.

Jeffrey I. Mechanick; Angelo Carpi

Opis

Written to keep up with the constant flow of information regarding new data, trials, and guidelines in thyroid cancer research, this book presents clinical guidelines governing diagnostics and therapeutics. It provides sufficient introductory chapters to explain methods used to translate experimental data into clinical practice based on molecular biology research and new clinical trial data. Chapters cover pathophysiology, systems biology, genetic and epigenetic alterations, risk stratification, and aspiration biopsy guidance. The reference also includes clinical case studies, which emphasize the emerging role of molecular medicine and looks at biotechnology innovations and novel medical imaging.

Spis treści

Principles of Translational Medicine and Applications to Thyroid Cancer Investigation. Systems Biology - An Overview. Genetic and Epigenetic Alterations in the MAP Kinase and PI3K/Akt Pathways in Thyroid Cancer. Genetic and Molecular Pathophysiology of Medullary Thyroid Carcinoma. Risk Stratification in Differentiated Thyroid Cancer. Clinical Practice Guidelines for Thyroid Cancer: Where Are We Now? Illustrative Case Studies of Thyroid-Carcinoma and the Emerging Role of Molecular Medicine. Advances In Thyroid Ultrasound For Detection And Follow-Up Of Thyroid Malignancies: Technical And Clinical Aspects. Multimodality Imaging and Aspiration Biopsy Guidance in the Perioperative Management of Thyroid Carcinoma. The Use of Diagnostic Radiotracers in Thyroid Cancer. PET-CT Scanning in the Management of Thyroid Cancer: Experience with a Cohort of 100 Patients. The Emerging Role of Percutaneous Needle Biopsy and Molecular Tumor Marker Analysis for the Preoperative Selection of Thyroid Nodules. Image-guided Mini-invasive Ablation of Thyroid Tumors and Distant Metastases. Thyroidectomy and Neck Exploration: New Surgical Approaches. Thyroid Surgery Performed under Local Anesthesia & Same-Day Surgery. The Use of Therapeutic Radiotracers in Thyroid Cancer. Role of Chemotherapy in Thyroid Cancer. Role of NF-KB In thyroid cancer. Biologically Targeted Therapies for Thyroid Cancers. Molecular Targeted Therapies of Medullary Thyroid Carcinoma.

O autorze

Angelo Carpi, MD is a clinical researcher at the University Hospital of Pisa. He is also an associate professor of Internal Medicine at Pisa University.

Jeffrey I. Mechanick, MD, Mount Sinai School of Medicine, New York City, is a Clinical Professor within the Department of Medicine, Division of Endocrinology, Diabetes, and Bone Disease at the Mount Sinai School of Medicine.