Thrombosis: Animal and Clinical Models

ISBN-13: 9781475712193 / Angielski / Miękka / 2012 / 337 str.

H. J. Day

Spis treści

to the Brook Lodge Workshop on Animal and Human Models in Thrombosis Research.- to the Brook Lodge Workshop on Animal and Human Models in Thrombosis Research.- Platelets in Thrombosis and Atherosclerosis.- Platelets and Thrombosis in the Development of Atherosclerosis and Its Complications.- Platelet Adherence to the Vessel Wall and to Collagen-Coated Surfaces.- Platelet Aggregation: Relevance to Thrombotic Tendencies.- Roles of Blood Flow in Platelet Adhesion and Aggregation.- Proteins Secreted by Platelets: Significance in Detecting Thrombosis.- Animal Models.- Animal Models: Importance in Research on Hemorrhage and Thrombosis.- Platelets, Endothelium, and Smooth Muscle Cells in Atherosclerosis.- Vessel Injury and Atherosclerosis.- Delayed Consequences of Endothelial Removal from Rabbit Aortae.- The Roles of Endothelium, Platelets,and Smooth Muscle Cells in Intimal Healing.- Interaction of Platelets with the Endothelium in Normal and von Willebrand Pigs.- Vessel Injury, Thrombosis, and Platelet Survival.- Clinical Models.- Venous Thrombosis: Mechanisms and Treatment.- Cardiac Thromboembolism: Evidence for Role of Platelets and Value of Platelet Suppressant Therapy.- Rationale for Antiplatelet Agents in Diabetic Vascular Disease.- The Role of Platelets in Transient Ischemic Attacks and Cerebral Vascular Accidents.- Influence of Antiplatelet Drugs on Platelet-Surface Interactions.- Discussions.- A Discussion of the Possible Significance of PGI2 in Thrombosis.- Relevance of in Vitro and Animal Models to Clinical Thrombosis.- A Discussion of Methods for Predicting Patients Who are Prone to Platelet Thromboembolism Including Measurements of Blood Components.