Thromboembolism: Aetiology, Advances in Prevention and Management

ISBN-13: 9789401161466 / Angielski / Miękka / 2012 / 348 str.

E. J. Brandas

Opis

When Mr. Nicolaides told me he was editing a book on Thromboem- bolism I was constrained to say "not another" for there have been a number of recent contributions to this field. Yet venous thromboembolism is a major accompaniment of nearly all forms of medical and surgical illness. All clinicians should know about it; all should be able to integrate their knowledge into clinical management. The problems remain of what to know and where to find it, particularly in a field which draws increasingly on other areas for its fundamentals and which is also changing fast. This volume is a brave endeavour to provide a view over the whole subject. It could not possibly succeed absolutely and both editor and contributors undoubtedly realise this. Nevertheless they have put at our disposal know- ledge of a wider kind than that available before and thus made it possible for the relatively inexpert such as myself to perceive how complex are the disturbances we produce by surgery or are produced by illness and where we can hope for advances in understanding and therapy in the future. A text of this kind hardly needs a foreword-it is of self evident value, although I expect the pace set by its writers and others in the field will, with the additional stimulus provided by this synthesis of ideas that has been achieved, soon require another volume. In the meantime it is a timely venture. H. A. F.

Spis treści

1. The problem of deep venous thrombosis and pulmonary embolism.- 2. Factors in the initiation of deep venous thrombosis.- 3. The nature of fibrinogen and fibrinogen-fibrin degradation products.- 4. Plasma fibrinogen chromatography, blood viscocity and venous thrombosis.- 5. Erythrocyte flexibility, blood fibrinogen and surgery.- 6. Abnormal blood viscosity and deep venous thrombosis.- 7. Platelets and venous thrombosis.- 8. The role of the vessel wall in deep venous thrombosis.- 9. Venous stasis in the lower limb.- 10. Origin and distribution of venous thrombi studied by postnortem intraosseous phlebography.- 11. Origin and distribution of thrombi in patients presenting with clinical deep venous thrombosis.- 12. Prospective identification of the pulmonary embolism-prone patient employing multi-variable risk factor analysis.- 13. Clinical Factors and the risk of deep venous thrombosi.- 14. A rational approach to prevention.- 15. Small dose subcutaneous heparin. A safe regimen.- 16. Small dose subcutaneous heparin in preventing deep venous thrombosis.- 17. The value of clinical signs in the diagnosis of deep venous thrombosis.- 18. The place of thrombolytic and defibrinating agents in the treatment of venous thromboembolism.- 19. The management of deep venous thrombosis.- 20. The management of pulmonary embolism.- 21. Thromboembolism in obstetric and gynaecological patients.