Therapy of Feto-Placental Insufficiency: I. International Symposium Parma, May 19th and 20th 1973

ISBN-13: 9783642660108 / Angielski / Miękka / 2011 / 356 str.

B. Salvadori

Opis

The progess in biological sciences and its applications in obstetrics in the last twenty years have formed the base for feto-placental semeiotics. In this way, it has been possible to diagnose placental insufficiency even in patients whose clinical conditions gave all the indications of a perfectly normal feto-placental condition. On the other hand, observations have shown that in certain conditions some deficiencies can im prove until normality is reached again. On the basis of the above one feels justified to talk about the therapy of feto-placental insufficiency. Until now this therapy has been aimed at the obstetrical pathology of the mother. Our aim is to illustrate the various steps which should be taken to execute an efficient therapy of the conditions relating to the pathology of the fetus, realizing full well that fetal pharmacology is only now being taken into consideration. The various steps to be taken, the length of therapy, and all the other correlated factors are still the object of individual ex periences, and we are fortunate to have amongst us researchers in this field who have accepted our invitation and can supply us with their personal experiences which can also be compared. The first international symposium on the therapy of feto-placental insufficiency has been organized in conjunction with the Samil-Pabyrn Foundation whom I would lik to thank, and especially so its president, Mrs. INGE SAXON-MILLS."

Spis treści

1st Session.- Plasma Oestriol in Obstetric Disease.- Validity of Cardiotocography in the Control of Feto-Placental Insufficiency. Preliminary Results.- The Diagnosis of “Small for Dates” Babies by the Cytological Examination of the Amniotic Fluid.- The Value of the Atropine Test in Therapeutic Orientation during Feto-Placental Insufficiency.- Assessment of the Value of Hormonal Assays and Ultrasonic Measurements in the Management of Placental Insufficiency.- Human Placental Lactogen as an Index of Placental Function: Plasma Measurements in Normal and Pathological Pregnancies.- Human Choriogonadotropin, Choriosomatomammotrophin and Fetal Nutrition.- The Clinical Value of the Placenta Lactogen in the Monitoring of Feto-Placental Disfunction.- Amniotic Fluid Analysis in Placental Insufficiency.- Thermostable Alkaline Phosphatases in Feto-Placental Insufficiency.- The Insulin Tolerance Test (I.T.T.) as a Basis for the Therapy of Placental Insufficiency.- Radioimmunologic Determination of Plasma Estriol in Pregnancy with a Specific Antiserum to Estriol.- Some Parameters of Feto-Placental Insufficiency.- Urinary Estriol as a Therapeutic Guide of Feto-Placental Failure in the Vasculo-Renal Hypertensive Syndrome of Pregnancy.- Diagnosis of Fetal Maturity by Biochemical and Cytological Studies.- Radioimmunological Determination of HPL, CAP and Daily Excretion of Urinary Oestriol in the Diagnosis of Chronic Placental Insufficiency.- Oestriol as Guide in the Treatment of Feto-Placental Insufficiency: Possibilities and Limits.- The Comparative Studies about the Estriol and HPL Production Rate in the Risk-Pregnancies.- 2nd Session.- The Pathology of Feto-Placental Insufficiency in Hypertensive Pregnancy.- Search for a Disturbance of Coagulation during Pregnancy in Cases of Intra-Uterine Growth Retardation.- Pathways of Glucose Metabolism in Human Placentae.- Experimental Investigations about Blood Flow and Oxygen-Consumption in Normal Pregnancy and Placental Dysfunction.- The Role of the Fetal Circulation in Placental Insufficiency.- Effect of an Adrenergic ß-Mimetic Compound (Ritodrine Hydrochloride) on the Feto-Placental Unit in Chronic Fetal Distress.- The Effect of a Beta-Mimetic (Ritodrine) on the Uterine Circulation during Normal and Pathological (Chronic Fetal Distress) Pregnancies. Therapeutic Implications.- The Effects of Beta-Mimetic (Ritodrine) during Pregnancy on Carbohydrate Metabolism and Hepatic Function of the Newborn Infant.- The Influence of a Beta-Mimetic on Placental Function-Tests.- Adrenergic ß-Mimetic-Compounds and Utero-Placental Blood Supply in Risk Pregnancies.- Early Trials in the Treatment of Placental Insufficiency with Ritodrine.- The Effect of Ritodrine on Infant Weight.- Oestrogen Excretion in a Group of 90 Pregnant Women Treated with Ritodrine.- The Influence of Some Preparations on the Feto-Placental Insufficiency.- Effects of a Beta-Adrenergic Agent on the Angiographically Visualized Uteroplacental Circulation in the Rhesus Monkey.- Orciprenaline in the Treatment of Premature Labour.- Betamimetic Drugs and the Feto-Placental Function.- Betamimetics and Placental Insufficiency Due to Uterine Hypoplasia.- Placental Function and Xanthinol-Nicotinate.- The Therapy of EPH Gestosis with Xantinol-Nicotinat: Short-Term Reactions of Blood Coagulation, Fibrinolysis and Human Placental Lactogen.- Ultrasound Study of the Effect of Hydergin on Feto-Placental Insufficiency.- Therapy of Feto-Placental Insufficiency with Xantinol-Nicothinate, Glucose and Insulin.- Maternal Excretion of Oestriol before and during Treatment of Placental Insufficiency with Xantinol-Nicotinate.- Xanthinol Nicotinate in the Treatment of EPH Gestosis.- The Treatment of EPH-Gestosis with Xantinol-Nicotinat-Alterations of HPL and Coagulation-Physiological Alterations over Long Periods.- The Behaviour of Serum Electrolytes, Serum Protein, and of the Substances to be Eliminated in the Case of Gestosis Treated with Xantinol-Nicotinat and Heparin.- Long Term Heparin Therapy for Placental Insufficiency.- 3rd Session.- Therapy of Feto-Placental Insufficiency during Pregnancy the Effects of Drugs on Placental Function.- Intra-Uterine Growth of Newborn Infants of Parma.- Maternal Hypertonic Dextrose Infusion in a Patient with Idiopathic Recurrent Placental Insufficiency and Low Urinary Oestrogens.- Improvements in Uterine-Placental Blood-Flow by Long-Term Treatment of EPH-Gestosis with Anti-Hypertensive Drugs.- Vasoactive or Phosphorilated Glycide Therapy in Placental Insufficiency.- Effects of Synthetic LH-RH on Serum Gonadotrophin, Prolactin and Chorionic Somatomammotrophin (HCS) during the Last Trimester of Pregnancy.- Trial of Treatment of Chronic Fetal Distress by Naftidrofuryl.- Chronic Fetal Distress. Research on Placental Blood Flow and Therapy.- The Effect of Abdominal Decompression on the Newborn.- The Use of Intermittent Abdominal Decompression and Oestriol Monitoring in the Treatment of Feto-Placental Insufficiency.- Intra-Amniotic Amino-Acid Injections.- The Effects of Maternal Infusions of L-Amino Acids as a Treatment of Chronic Fetal-Placental Insufficiency.- Plasma Amino-Acids in “Small for Date” Newborn Infants.- Treatment of Severe Feto-Placental Insufficiency by Means of Intraamniotic Injection of Amino-Acids.- Fetal and Maternal Uptake of Se 75 Methionine after Intra-Amniotic Injection in Rabbits.- Exogenous Progesterone and Feto-Placental Function.- Human Placental Lactogen Production in Vitro 1. Dynamic Studies on Normal-Term Placentals after Stimulation with 17-?-Oestradiol.- Daily Urinary Hormonal Pattern Following 17 ß-Oestradiol Treatment of Prolonged Pregnancies.- Experiences with Administration of Dehydroepiandrosterone-Sulfate and Pregnenolone in Cases of Feto-Placental Insufficiency.- Variation in Maternal Urinary Excretion of Total Oestrogens Following ACTH Administration to the Fetus in Utero.- A Study of Feto-Neonatal Effects of Maternal Administration of Dehydroepiandrosterone Sulphate (DEAS) in Rats.- Variation in Maternal Urinary Excretion of Total Oestrogens Following Intra-Amniotic Administration of Dehydroepiandrosterone.- Levels of Serum Unconjugated Oestrogens after DHEA-S Loading Tests in Human Pregnancy.- The Reliability of a Placental Function Test Using Dihydroepiandrosterone Sulphate (DHEA-S).- 21- and 18-C Urinary Steroids after the Oral Administration of DHA-S in Pregnancy.- Subject-Index.