ISBN-13: 9781009073646 / Angielski / Miękka / 2022 / 75 str.
This Element reviews key aspects of RAS biochemistry that are directly relevant to understanding the newly available RAS inhibitors.
Introduction; RAS Biology; Oncogenic RAS; RAS Targeting; Downstream Targeting; Upstream Targeting; Targeting Specific RAS Mutants; KRAS G12C Targeting; Direct Targeting of Other RAS Proteins; KRAS G12R Pancreatic Cancer; KRAS G13D Colorectal Cancer; Summary; References.
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