Therapeutic Drug Monitoring: Newer Drugs and Biomarkers

ISBN-13: 9780443186493 / Angielski

Amitava Dasgupta

Spis treści

1. An introduction to therapeutic drug monitoring: Commonly monitored and less commonly monitored drugs 2. Effects of Pre-Analytical Variables in Therapeutic Drug Monitoring 3. Analytical techniques in therapeutic drug monitoring 4. Drug monitoring in alternative specimens (oral fluid and dried blood spot) 5. Clinical Utility of Monitoring Free Drug Concentrations 6. Monitoring of Classical and Newer Anticonvulsants 7. Challenges in Therapeutic Drug Monitoring of Digoxin and other Cardioactive Drugs 8. Guidelines for Monitoring Vancomycin, and Aminoglycosides and other antibiotics 9. Challenges in Therapeutic Drug Monitoring of Classical Tricyclic and Newer Antidepressants 10. Therapeutic drug monitoring of antiretroviral agents in the management of human immunodeficiency virus 11. Therapeutic drug monitoring of selected antifungal agents 12. Therapeutic drug monitoring of selected of direct oral anticoagulants 13. Drug Monitoring in Pain Management 14. An Introduction to Personalized Medicine 15. Analytical techniques including microarray technology in pharmacogenomics testing 16. Pharmacogenomics and Warfarin Therapy 17. Drug hypersensitivity linked to genetic variation of HLA 18. Therapeutic drug monitoring and pharmacogenomics issues of selected anticancer drugs 19. Challenges in monitoring immunosuppressants: limitation of immunoassays and application of LC/MS 20. Biomarkers: The link between therapeutic drug monitoring and pharmacogenomics of immunosuppressants 21. Pharmacodynamic monitoring as an integral part of therapeutic drug monitoring 22. Role of therapeutic drug monitoring to identify clinically significant drug-herbal supplement interaction