Therapeutic Applications of Adenoviruses

ISBN-13: 9780367658182 / Angielski / Miękka / 2021 / 256 str.

Philip Ng; Nicola Brunetti-Pierri

Opis

This book will review the life history and immune responses to adenoviruses as well summarize various therapies implemented with the use of adenoviruses.

Spis treści

Adenovirus Biology: Virus structure and life cycle. Immune responses to adenovirus. Helper-dependent adenoviral vectors for gene and cell therapy. Genetic and capsid modified Adenovirus. Adenovirus for vaccination. FGAd and HDAd. Adenovirus vectors for cancer therapy. Adenovirus-based hybrid vectors. FDA expectations and requirements of adenoviral products.

O autorze

Philip Ng is jointly an Associate Professor of Department of Molecular and Human Genetics and the Program in Translational Biology & Molecular Medicine at the Baylor College of Medicine. He is interested in developing gene therapies for genetic diseases using helper-dependent adenoviral vectors (HDAd).

Nicola Brunett-Pieri is an Associate Professor in the Department of Translational Medicine at Federico II University in Naples and an Associate Investigator at Telethon Institute of Genetics and Medicine (TIGEM).