The Stomach: Physiology, Pathophysiology and Treatment

ISBN-13: 9783540566137 / Angielski / Miękka / 1993 / 396 str.

W. Domschke; S. J. Konturek

Opis

On the subject of stomach and gastric diseases, current cli- nical, morphological, pharmacological, biochemical as well as cellular and molecularbiological aspects will be presen- ted. The articles of the first part of this book will discuss the normal functions of the stomach (such as motility, secre- tion, tissue regeneration etc.). The second part deals with pathophysiological aspects (such as inflammation, ulceration and tumor formation) and modern possibilities of treatment. The authors aim at gaining a deeper knowledge of the sto- mach, its physiology and pathophysiology in order to use this knowledge for the better of their patients."

Spis treści

Gastric Physiology and Pathophysiology.- Parietal Cell Receptors of Acid Secretion.- Structural and Functional Significance of the Gastric H+,K+-ATPase.- New Insights into the Regulation of Gastric Secretion in Duodenal Ulcer Patients.- Kinetics of the Gastric Epithelial Cells.- Trophic Effects of Gastrin: Therapeutic and Pathophysiological Implications.- Gastric Mucosal Damage and Protection: Involvement of Novel Endothelium - Derived Mediators.- Gastroduodenal Alkaline Secretion and Its Pathophysiological Significance.- Role of Lipids and Membrane Biogenesis in the Process of Mucus Secretion.- Mucus and Gastric Mucosal Protection.- Gastric Mucosal Blood Flow and Its Role in the Pathogenesis of Acute and Chronic Ulceration.- Growth Factors in Gastric Mucosal Integrity, Protection and Healing of Acute and Chronic Ulcerations.- Cellular Mechanisms of Gastric Ulcer Healing.- Role of bFGF and Angiogenesis in Ulcer Healing and the Treatment of Gastritis.- Helicobacter Pylori: Pathogenic Mechanisms.- Gastric Diseases and Treatment.- Epidemiology of Ulcer Disease.- NSAIDs and Gastroduodenal Lesions: How Big a Problem and How to Prevent?.- Therapeutic Strategy in Gastro-oesophageal Reflux Disease.- The Management of Zollinger-Ellison Syndrome.- Medical Treatment of Acute Peptic Ulceration.- Rational Long-Term Therapy of Peptic Ulcer Disease.- Endoscopic Diagnosis and Treatment of Bleeding Gastroduodenal Ulcers.- Are There Any Indications for Surgery in Peptic Ulcers Today?.- Nonulcer Dyspepsia: A Diagnostic and Therapeutic Challenge.- Endosonography of the Stomach and Its Disorders.- Operative Endoscopy in the Stomach: Polypectomy.- Operative Endoscopy in the Stomach: Percutaneous Endoscopic Gastrostomy.- Operative Endoscopy in the Stomach: Cystogastric Pancreatic Drainage.- Laser Treatment of Early Gastric Carcinoma in Japan: An Overview.- Photodynamic Therapy of Gastric Malignancies: Current Status and Future Prospects.- Extended Lymph Node Dissection for Advanced Gastric Cancer and Endoscopic Surgery for Early Gastric Cancer.- Stage-Adjusted Chemotherapy of Gastric Cancer.