The Steric Factor in Medicinal Chemistry: Dissymmetric Probes of Pharmacological Receptors

ISBN-13: 9781489923998 / Angielski / Miękka / 2013 / 570 str.

A. F. Casy

Opis

'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in which he has been active and successful for many years both as a teacher and a researcher. Written for graduate students and research workers in medicinal chemistry and pharmacology, this book will contribute significantly towards a better education of scientists by removing the fear of stereochemistry caused by ignorance, moderating the overconfidence of possible zealots, and outlining a broader context.'-from the foreword by Bernard Testa

Spis treści

Introduction. Nomenclature and Methodology. Pharmacokinetics. Adrenergic Ligands. Adrenoceptor Antagonists. Dopamine and Dopaminergic Agonists. Dopamine Antagonists. Cholinergic Agonists. Muscarinic Agonists. Ligands of Nicotinic Cholinergic Receptors Including Neuromuscular Blocking Agents. Histamine Receptors. 5Hydroxytryptamine Ligands. Opioid Ligands I. Opioid Ligands II. Index.