Part I. The Science of Learning and Development in the Twenty-First Century: 1. Introducing the science of learning and development in education; 2. Hebb's Postulate and the learning brain; 3. The dynamics of learning and development; 4. The active learner: working memory, metacognition and brain research; 5. The dynamics of literacy and numeracy learning and development; Part II. The Emotional, Cultural, Moral and Empathic Brain: 6. The emotional brain, learning and development; 7. The social and cultural brain, learning and development; 8. The dynamic, moral, empathetic brain; Part III. Learning, Wellbeing and the Ecology of Learning Environments: 9. The learner, embodied cognition and the affordance of learning environments; 10. Science of Learning, assessment and feedback; 11. Student wellbeing and the science of learning and development.