Part I. The Ovarian Follicular Apparatus: Operational Characteristics 1. Follicle Selection in Mammalian Ovaries 2. Regulation of follicle formation and development by ovarian signaling pathway 3. Human Folliculogenesis Revisited: The Menstrual Cycle Visualized by Ultrasonography 4. Development of the Mammalian Ovary and Follicles 5. Organization of Ovarian Steroidogenic Cells and Cholesterol Metabolism 6. Inhibin, Activin and Follistatin in Ovarian Physiology 7. Cell-cell Interactions in the Ovarian Follicles: Role of TGF-beta Superfamily Members 8. Mutations and Polymorphisms, and their Functional Consequences, in Gonadotropin and Gonadotropin Receptor Genes 9. Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease Part II. Oocyte Maturation and Ovulation 10. Mammalian Oogenesis - the fragile foundation of the next generation 11. Regulation of Mammalian Oocyte Maturation 12. Oocyte Meiotic Maturation 13. Gene Expression During Oogenesis and Oocyte Development Part III. The Corpus Luteum 15. Molecular Regulation of Progesterone Production in Corpus Luteum 16. Corpus Luteum Formation 17. Luteolysis and The Corpus Luteum of Pregnancy Part IV. Novel Experimental Models 18. Transgenic Mouse Models in the Study of Ovarian Function 19. Genome-Wide Association Studies of Ovarian Function Disorders 20. Mitchondria Research in Human Reproduction 21. The Role of Mitochondria in Reproductive Function and Assisted Reproduction Part V. Human Ovarian Pathophysiology: Select Aspects 22. Ovarian Hyperstimulation Syndrome 23. The Role of GnRH Agonist Triggering in GnRH Antagonist-Based Ovarian Stimulation Protocols 24. The Ovarian Factor in Assisted Reproductive Technology 25. The Role of Antimullerian Hormone in Assisted Reproduction 26. Polycystic Ovary Syndrome 27. Genetic and Environmental Factors in the Aetiology of Polycystic Ovary Syndrome 28. Germ Cell Failure and Ovarian Resistance: Human Genes and Disorders 29. Environmental Contaminants and Ovarian Toxicity 30. Autologous Transplantation of Human Ovarian Tissue 31. Oncofertility: Preservation of ovarian function after a cancer diagnosis Part VI. Human Ovarian Cancer 32. Ovarian cancers: their varied origins and pathologically implicated microenvironment 33. Phenotypic Plasticity and the Origins and Progression of Ovarian Cancer 34. Novel Therapeutic Approaches and Targets for Ovarian Cancer 35. Molecular and Cellular Basis of Chemoresistance in Ovarian Cancer