The Neuroscience of Parkinson's Disease

ISBN-13: 9780128159583 / Angielski / Other / 2020

Colin R. Martin; Victor R. Preedy

Recenzje

"This is an outstanding addition to the literature that provides a comprehensive, contemporary, evidence-based review of Parkinson's disease. It will be a worthy inclusion for libraries of any students, researchers, and physicians involved in Parkinson's disease treatment or research." --Doody

Spis treści

Section 1 Parkinson's Disease: Introductory Chapters1. A Short History of Parkinson's Disease - from early 19^th century and afterwards - an overview2. Living with Parkinson's disease - from financial to emotional3. The epidemiology of Parkinson's disease - an overview4. Clinical Features of Parkinson's disease - an overview5. The natural history of Parkinson's disease - an overview6. The prognosis of Parkinson's disease - an overview7. The neurobiology of Parkinson's disease - an overview8. The pathophysiology of Parkinson's disease - an overview9. Molecular and cellular mechanisms associated with Parkinson's disease - synuclein, amyloid protein, oligomers and beyond10. Quality of life in Parkinson's disease11. Gait in untreated Parkinson's disease12. Levodopa-induced dyskinesias13. Tremor in Parkinson's disease14. The impact of Parkinson's disease on the family and careers

Section 2 Biomarkers and Diagnosis15. Tissue biopsies as biomarkers in Parkinson's disease16. Spinal fluid for biomarker discovery in Parkinson's disease17. Clinical biomarkers in prodromal Parkinson's disease18. The diagnosis of Parkinson's disease19. Proteomics in Parkinson's disease20. MicroRNAs as biomarkers in Parkinson's diseases21. Phenotyping in Parkinson's disease22. Diagnosis of speech disorders in Parkinson's disease23. Identifying dementia in Parkinson's disease24. Diagnosis of sleep disturbances in Parkinson's disease25. Diagnosis of Parkinson's disease using magnetic resonance imaging26. Use of ultrasound as a diagnostic tool in Parkinson's disease27. Use of single-photon emission computerized tomography (SPECT) as a diagnostic tool in Parkinson's disease28. Use of positron emission tomography (PET) as a diagnostic tool in Parkinson's disease

Section 3 Pharmacological Treatments for Parkinson's Disease29. Dopamine Agonists and Parkinson's disease - an overview30. Management with Levodopa in Parkinson's disease31. Management with ripinirole in Parkinson's disease32. Management with pramipexole in Parkinson's disease33. Management with rotigotine in Parkinson's disease34. Management with apomorphine in Parkinson's disease35. Management with MAO-B Inhibitors in Parkinson's disease36. Management with COMT inhibitors in Parkinson's disease37. Management with anticholinergics in Parkinson's disease38. Management with amantadine in Parkinson's disease

Section 4 Novel and Non-Pharmacological Therapies For Parkinson's Disease39. Treatment with chelator in Parkinson's disease40. Treatment with deep brain stimulation in Parkinson's disease41. Olive leaf extract usage as an antioxidant and applications to Parkinson's disease42. Treatment with Vitamin D for Parkinson's disease43. Chemogenetics and applications for Parkinson's disease44. Flavonoids and naringin usage in Parkinson's disease45. Stem cells and applications to Parkinson's disease46. Treatment with cannabis for Parkinson's disease47. Treating sleep problems in Parkinson's disease48. Perioperative treatments of Parkinson's disease49. Exercise and Parkinson's disease50. Molecular aspects: CB2 receptors and neuroprotection in Parkinson's disease