The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

ISBN-13: 9781441942821 / Angielski / Miękka / 2010 / 490 str.

Bharat B. Aggarwal; Young-Joon Surh; S. Shishodia

Opis

Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. More than 1500 papers published within last half a century has revealed that curcumin has a potential in the treatment of wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer, psoriasis etc, through modulation of numerous molecular targets. This is the first monograph to deal specifically with this subject.

Spis treści

Curcumin: The Indian Solid Gold .- Highly Active Anti-Cancer Curcumin Analogs.- Antioxidant And Anti-Inflammatory Properties Of Curcumin.- Modulation Of Transcription Factors By Curcumin .- Cancer Chemopreventive Effects Of Curcumin.- Anti-Tumor, Anti-Invasion And Antimetastatic Effects Of Curcumin.- Curcumin As An Inhibitor Of Angiogenesis.- Neuroprotective Effects Of Curcumin.- Regulation Of Cox And Lox By Curcumin.- Molecular Targets Of Curcumin.- Cell Growth Regulation.- Curcumin As Chemosensitizer.- Radioprotection And Radiosensitization By Curcumin.- Immunomodulation By Curcumin.- Beneficial Role Of Curcumin In Skin Diseases.- Cardioprotective Effects Of Curcumin.- Protection From Acute And Chronic Lung Diseases By Curcumin.- Nephroprotective And Hepatoprotective Effects Of Curcuminoids.- Curcumin And Autoimmune Disease.- Pharmacokinetics And Pharmacodynamics Of Curcumin.- Clinical Studies With Curcumin.