The Mathematical Theory of Selection, Recombination, and Mutation

ISBN-13: 9780471986539 / Angielski / Twarda / 2000 / 424 str.

R. Burger; Reinhard Burger;Burger

Opis

"It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA
Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail.
* Provides a unified, self-contained and in-depth study of the theory of multilocus systems
* Introduces the basic population-genetic models
* Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection
* Summarizes important results from more demanding sections in a comprehensible way
* Employs a clear and logical presentation style
Following an introduction to elementary population genetics and discussion of the general theory of selection at two or more loci, the author considers a number of mutation-selection models, and derives the dynamical equations for polygenic traits under general selective regimes. The final chapters are concerned with the maintenance of quantitative-genetic variation, the response to directional selection, the evolutionary role of deleterious mutations, and other topics.
Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in-depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology.

Recenzje

"an excellent reference volume" (Zentralblatt Math, Vol. 959, No. 9 2001)

"...Burger′s text is without equal. This is a book that should grace shelves in both mathematics and biology...that provides yet another point of contact for two communities whose interests can only grow closer..." (SIAM Review, Vol. 43, No. 4)

"This is a book that should grace shelves in both mathematics and biology departments." (Society for Industrial Applied Mathematics Review, Vol.43. No.4 2001)

"...it is such a comprehensive compendium that it will become the first port of call for any mathematician..." (The Statistician, Vol. 51, No.2, 2002)

"...the models described here provide a fundamental underpinning to our understanding of the properties of quantitative genetic variation...." (Journal of Evolutionary Biology, Vol. 14, 2001)

"...a major and significant piece of work..." (Genetical Research)

Spis treści

Elementary Population Genetics.

Selection at Two or More Loci.

Classical Mutation–Selection Models.

Mutation–Selection Models for Quantitative Traits.

Dynamical Equations for Quantitative Traits under Selection.

Stabilizing Selection and Genetic Variation in Large Populations.

Quantitative Variation and Selection.

Appendix.

References.

Indexes.

Blurb

The Mathematical Theory of Selection, Recombination, and Mutation R. Bürger University of Vienna, Austria "It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail.
∗ Provides a unified, self–contained and in–depth study of the theory of mutilocus systems
∗ Introduces the basic population–genetic models
∗ Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection
∗ Summarizes important results from more demanding sections in a comprehensible way
∗ Employs a clear and logical presentation style
Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in–depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology. Visit Our Web Page! http://www.wiley.com/