The Kinesin Superfamily Handbook: Transporter, Creator, Destroyer

ISBN-13: 9781032241326 / Angielski / Miękka / 2022 / 186 str.

Claire T. Friel

Opis

This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for reseachers looking to make comparisons between different familiies, for specific information on a family, or simply for an overview of the kinesin superfamily.

Spis treści

Contents

Acknowledgements....................................................................................................ix

Editor bio...................................................................................................................xi

List of Contributors................................................................................................. xiii

Chapter 1 Introduction to the Kinesin Superfamily..............................................1

Hannah R. Belsham and Claire T. Friel

Chapter 2 The Kinesin-1 Family: Long-Range Transporters.............................. 15

David D. Hackney and Alison E. Twelvetrees

Chapter 3 The Kinesin-2 Family: Transporters................................................... 33

William O. Hancock

Chapter 4 The Kinesin-3 Family: Long-Distance Transporters.......................... 41

Nida Siddiqui and Anne Straube

Chapter 5 The Kinesin-4 Family......................................................................... 55

Claire T. Friel

Chapter 6 The Kinesin-5 Family: Transporters and Creators.............................65

Mary Popov, Alina Goldstein-Levitin and Larisa Gheber

Chapter 7 The Kinesin-6 Family.........................................................................83

Claire T. Friel

Chapter 8 The Kinesin-8 Family.........................................................................87

Tianyang Liu, Alejandro Peña, Fiona Shilliday, and

Carolyn A. Moores

Chapter 9 The Kinesin-13 Family: Specialist Destroyers.................................. 101

Julie P. Welburn and Claire T. Friel

Chapter 10 The Kinesin-14 Family...................................................................... 115

Marcus Braun, Stefan Diez and Zdenek Lansky

Chapter 11 The Kinesin-15 Family...................................................................... 135

Hauke Drechsler, Jaspreet Singh Grewal and Andrew D. McAinsh

Chapter 12 The Kinesin-16 Family...................................................................... 155

Hanan M. Alghamdi and Claire T. Friel

Chapter 13 Other Kinesin Families..................................................................... 161

Claire T. Friel

Chapter 14 Summary and Future Perspectives.................................................... 165

Claire T. Friel

Index....................................................................................................................... 167

O autorze

Claire T. Friel earned a BSc in Biochemistry from the University of Glasgow, UK, and carried out her PhD work on protein folding kinetics in the laboratory of Sheena Radford at the University of Leeds, UK. In 2006, she joined the group of Jonathon Howard at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. There, she solved the ATP turnover cycle of the microtubule depolymerising Kinesin-13, MCAK, and developed an interest in the kinesin superfamily of molecular motors. Since 2011, Claire has held the position of Assistant Professor at the University of Nottingham, UK. The research goals of the Friel lab are to understand the relationship between the kinesin motor domain sequence and the many functional properties of the kinesin superfamily and to understand the molecular mechanisms of proteins that regulate microtubule dynamics.