The Inflammatory Myopathies

ISBN-13: 9781603278287 / Angielski / Twarda / 2009 / 342 str.

Lawrence Kagen

Opis

This book is dedicated to our readers with the intention of providing an informative exposition of the myositis syndromes. It is also presented in the hope that perhaps it may serve to inspire and stimulate discussion and research into these disabling disorders. Included are descriptions of clinical features, differential diagnosis, pathogenetic mechanisms, and approaches to therapy. Current concepts of classi- cation and diagnostic techniques are also presented. The production staff at Humana Springer, especially Ms. F. Louie and Ms. C. Walsh, have been instrumental and invaluable in allowing this work to see the light of day. Above all, the scholarly essays of the contributing authors are acknowledged with gratitude. They have given this volume its character and existence. New York, NY Lawrence J. Kagen v Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Evaluation of the Patient . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Lawrence J. Kagen 2 Classification of Idiopathic Inflammatory Myopathies . . . . . . . . . . . . . . . . . . . . . . . . 15 Frederick W. Miller 3 The Inflammatory Milieu: Cells and Cytokines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Ann M. Reed and Thomas A. Griffin 4 Juvenile Dermatomyositis: An Update on Clinical and Laboratory Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 Lauren M. Pachman 5 Inclusion Body Myositis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Lawrence J. Kagen 6 The Role of Muscle Biopsy in the Diagnosis of Inflammatory Myopathy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 Sakir Humayun Gultekin 7 Electromyography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1 1 Hans L. Carlson 8 Magnetic Resonance Imaging of Myopathies and Myositis . . . . . . . . . . . . . . . . . 127 Carolyn M. Sofka 9 Ultrasound in the Evaluation of the Inflammatory Myopathies . . . . . . . . . 147 Ronald S. Adler and Giovanna Garofalo vii viii Contents 10 Serological Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165 Ira N.

Recenzje

From the reviews:

"This overview of the inflammatory myopathies goes through the pathophysiology, diagnostic testing, imaging, and treatment of these diseases, with up-to-date references. ... The book is written for rheumatologists and possibly neuromuscular specialists ... . This well-written book provides a detailed and current view of the inflammatory myopathies and the evidence-based approach to them. ... the authors and editor have done a laudable job of compiling the most current and pertinent information available." (Chris Phillips, Doody's Review Service, December, 2009)

"In 11 chapters the authors review recent knowledge on the above group of disease, including dermatomyositis. ... With many illustrations, most in color. Of interest to rheumatologists, neurologists and physical therapists." (Pediatric Endocrinology Reviews, Vol. 8 (2), December, 2010)

"This book provides a comprehensive review of the most common and uncommon inflammatory myopathies in eighteen well organized chapters, including a step-by-step review of the skeletal and extra-skeletal manifestations, diagnostic criteria, environmental risk factors, and treatment outcomes. Each chapter is written by an expert in a different medical field ... . Radiologists, rheumatologists, neurologists and other healthcare professionals involved in the treatment in afflicted patients should find this book very useful and informative." (American Journal of Neuroradiology, October, 2009)

Spis treści

Chapter 1 Evaluation of the Patient Lawrence J. Kagen Chapter 2 Classification of Idiopathic Inflammatory Myopathies Frederick W. Miller Chapter 3 The Inflammatory Milieu: Cells and Cytokines Ann M. Reed and Thomas A. Griffin Chapter 4 Juvenile Dermatomyositis: An Update on Clinical and Laboratory Findings Lauren M. Pachman Chapter 5 Inclusion Body Myositis Lawrence J. Kagen Chapter 6 The Role of Muscle Biopsy in the Diagnosis of Inflammatory Myopathy Sakir Humayun Gultekin Chapter 7 Electromyography Hans L. Carlson Chapter 8 Magnetic Resonance Imaging of Myopathies and Myositis Carolyn M. Sofka Chapter 9 Ultrasound in the Evaluation of the Inflammatory Myopathies Ronald S. Adler and Giovanna Garofalo Chapter 10 Serological Findings Ira N. Targoff Chapter 11 Antisynthetase Syndrome Galina S. Marder and Robert Greenwald Chapter 12 Pulmonary Manifestations of Inflammatory Myopathy Eun Ha Kang and Yeong Wook Song Chapter 13 Dermatological Manifestations of Dermatomyositis Mark Kagen Chapter 14 The Differential Diagnosis of Inflammatory Myopathy Michael Rubin and Asaf Klein Chapter 15 Outcomes and Assessment for Inflammatory Muscle Disease Lisa G. Rider Chapter 16 Muscle Strength and Exercise in Patients with Inflammatory Myopathies Helene Alexanderson and Ingrid E. Lundberg Chapter 17 The Risk of Malignancy in Patients with Dermatomyositis and Polymyositis Alan N. Baer and Robert L. Wortmann Chapter 18 Treatment Stephen J. DiMartino

Blurb

Representing the most up-to-date knowledge of this family of diseases, this book presents a comprehensive overview of the inflammatory myopathies, including dermatomyositis, polymyositis and inclusion body myositis. The Inflammatory Myopathies covers clinical presentation, diagnosis and classification, ongoing assessment, treatment and pathogenesis. Physical findings, laboratory studies, imaging modalities and biopsy are discussed. The role and mechanism of the inflammatory response is also explored. The Inflammatory Myopathies is the gold-standard in the field, an essential resource for rheumatologists, neurologists and all healthcare professionals who treat afflicted patients.