1. Introduction: The human hypothalamus and neuropsychiatric disorders SECTION 21 Trauma and iatrogenic disorders 2. Chronic traumatic encephalopathy and the nucleus basalis of Meynert SECTION 22 Neurobehavioral disorders 3. Hypothalamic stress systems in mood disorders 4. Light therapy for mood disorders 5. Neurobiology of peripartum mental illness 6. The hypothalamo-pituitary-adrenal axis and the autonomic nervous system in burnout 7. Posterior hypothalamus as a target in the treatment of aggression: From lesioning to deep brain stimulation 8. The implications of hypothalamic abnormalities for schizophrenia 9. The promiscuity of the oxytocin-vasopressin systems and their involvement in autism spectrum disorder SECTION 23 Epilepsy 10. Gelastic seizures and the hypothalamic hamartoma syndrome: Epileptogenesis beyond the lesion? 11. The interactions between reproductive hormones and epilepsy SECTION 24 Neurodegenerative disorders 12. Alternative splicing in aging and Alzheimer's disease: Highlighting the role of tau and estrogen receptor a isoforms in the hypothalamus 13. Cholinergic neurodegeneration in Alzheimer disease mouse models 14. Autonomic disorders in Parkinson disease: Disrupted hypothalamic connectivity as revealed from resting-state functional magnetic resonance imaging 15. Hypothalamic a-synuclein and its relation to autonomic symptoms and neuroendocrine abnormalities in Parkinson disease 16. Lewy bodies in the olfactory system and the hypothalamus 17. Hypothalamic pathology in Huntington disease 18. Endocrine dysfunction in adrenoleukodystrophy 19. Hypothalamic symptoms of frontotemporal dementia disorders SECTION 25 Olfactory system 20. The vomeronasal organ: History, development, morphology, and functional neuroanatomy 21. Pheromone effects on the human hypothalamus in relation to sexual orientation and gender 22. Kallmann syndrome and idiopathic hypogonadotropic hypogonadism: The role of semaphorin signaling on GnRH neurons 23. Olfaction as an early marker of Parkinson's disease and Alzheimer's disease SECTION 26 Autonomic and sleep disorders 24. The hypothalamus and its role in hypertension 25. The heart is lost without the hypothalamus 26. Sleep disorders and the hypothalamus SECTION 27 Addiction and pain 27. Molecular genetics of neurotransmitters and neuropeptides involved in Internet use disorders including first insights on a potential role of hypothalamus' oxytocin hormone 28. The neurobiology of cluster headache SECTION 28 Critical care and brain-death 29. Endocrine interventions in the intensive care unit 30. Hypothalamic function in patients diagnosed as brain dead its practical consequences