The Handbook of Polyhydroxyalkanoates: Kinetics, Bioengineering, and Industrial Aspects

ISBN-13: 9780367275624 / Angielski / Twarda / 2020 / 514 str.

Martin Koller

Opis

This volume covers kinetics, bioengineering and industrial aspects and focusses on thermodynamic and mathematical considerations of PHA biosynthesis, bioengineering aspects regarding bioreactor design and downstream processing for PHA recovery from microbial biomass.

Spis treści

Chapter 1: An Introduction to the Thermodynamics Calculation of PHA Production in Microbes1.1Introduction1.2Introduction to Thermodynamics and its Application to PHA Synthesis1.3PHA Synthesis Under Aerobic Conditions1.4PHA Synthesis under Anaerobic Conditions1.5Conclusions and OutlookReferences Chapter 2: Mathematical Modelling for Advanced PHA Biosynthesis2.1Introduction2.2Kinetics of PHA Biosynthesis2.3Mathematical Modelling of PHA Biosynthesis2.4Metabolic Pathway and Flux Analysis Methods in Modelling of PHA Biosynthesis2.5Conclusions and OutlookReferences Chapter 3: Interconnection between PHA and Stress Robustness of Bacteria3.1Importance of Stress Robustness for Bacteria3.2PHA and stress induced by high temperature3.3Protective Functions of PHA Against Low Temperature and Freezing3.4Osmoprotective Function of PHA Granules3.5Protective Function of PHA Against Radiation3.6Oxidative Stress and PHA3.7Stress Induced by Heavy Metals and other Xenobiotics and PHA Metabolism3.8Conclusions and OutlookReferences Chapter 4: Linking Salinity to Microbial Biopolyesters Biosynthesis: Polyhydroxyalkanoate Production by Haloarchaea and Halophilic Eubacteria4.1Introduction4.2Halophilic microbes producing PHA4.3PHA production by Halophilic Archaea (“Haloarchaea”)4.4Gram-Negative Halophilic Eubacteria as PHA Producers4.5Gram-positive halophilic PHA producers4.6Conclusions and OutlookReferences Chapter 5: Role of Different Bioreactor Types and Feeding Regimes in Polyhydroxyalkanoates Production5.1 Introduction5.2 Process Optimization for PHA Production5.3 Reactor Operating Strategies for PHA Production5.4 Nutrient Feeding Regimes for PHA Production5.5 Conclusions and OutlookReferences Chapter 6: Recovery of Polyhydroxyalkanoates from Microbial Biomass6.1 Introduction6.2 PHA Recovery Methods6.3 Mechanical Methods6.4 Biological Recovery Methods 6.5 Physical Purification Methods6.6 Conclusions and OutlookReferences Chapter 7: Polyhydroxyalkanoates by Mixed Microbial Cultures: The Journey so Far and Challenges Ahead7.1The Journey so Far7.2Definition of MMCs7.3 A Little Bit of History7.4 What Do We Know about PHA by MMCs?7.5 Presently Accepted Strategies7.6.Microorganisms and Metabolism7.7.Challenges Ahead7.8.Conclusions and OutlookReferences Chapter 8: PHA Production by Microbial Mixed Cultures and Organic Waste of Urban Origin: Pilot Scale Evidences8.1. Introduction8.2. MMC-PHA Production in the Urban Biorefinery Model8.3. Pilot Scale Studies for Urban Waste Conversion into PHA8.4 Conclusions and OutlookReferences Chapter 9: Production Quality Control of Mixed Culture Poly(3-Hydroxbutyrate-co-3-Hydroxyvalerate) Blends Using Full-Scale Municipal Activated Sludge and Non-Chlorinated Solvent Extraction9.1 Introduction9.2 Materials and methods9.3 Results and Discussion9.4 Conclusions and OutlookReferences Chapter 10: Economics and Industrial Aspects of PHA Production10.1 Introduction10.2 A Brief History of PHA10.3 Physical Properties10.4 Cost and EconomicsReferences Chapter 11: Next Generation Industrial Biotechnology (NGIB) for PHA Production11.1 Introduction11.2. Chassis for NGIB11.3. Production of PHA by Halophiles 11.4. Genetic Tools for Halophile Engineering11.5. Engineering Halomonas spp. for PHA production11.6. Morphology Engineering for Easy Separation11.7. Conclusions and OutlookReferences Chapter 12: PHA Biosynthesis Starting from Sucrose and Materials from Sugar Industry12.1. Introduction of Sucrose for PHA production12.2. Use of Molasses for PHA Production12.3. Bacterial strains for PHA production from sucrose12.4. Setting up a biorefinery to produce PHA in Brazil12.5. A new Biorefinery for PHA Production in Brazil12.6. Conclusions and OutlookReferences Chapter 13: LCA, Sustainability and Techno-economic Studies for PHA Production13.1 Introduction13.2 Economic Analysis13.3 Sustainability of PHA Production13.4. Conclusions and OutlookReferences