The Genus Yersinia: Entering the Functional Genomic Era

ISBN-13: 9780306477591 / Angielski / Twarda / 2003 / 490 str.

Mikael Skurnik; Jose Antonio Bengoechea; Kaisa Granfors

Opis

For the eighth time the yersiniologists all over the world gathered together when the International Symposium on Yersinia was organized by University of Turku and Turku Microbiology Society in Turku, Finland. Over 250 delegates from 28 countries attended the Symposium. The Symposium logo (Picture 4, next page) presents a bacteriophage attached to the surface of the bacterium. One can easily imagine that most of the aspects covered in this Symposium are included in the logo: the bacteriophage genome encodes for structural proteins, adhesins and effector proteins that interact with the host cell in most intricate ways to carry out their mission. Life of the bacteriophage depends on the tightly regulated interplay between the phage and the host proteins. This all is also true between Yersinia and the different hosts and environments it encounters during its life cycle. This Symposium Proceedings volume is based on the oral and poster presentations given during the Symposium. The volume has been divided into six parts covering topics such as genomics, surface structures, bacteriophages, molecular and cellular pathogenesis, molecular epidemiology and diagnostics, gene regulation, clinical aspects and vaccines. These topics reflect righteously the present trends in the bacteriology research.

Spis treści

Part I: Evolution And Genomics. 1. Evolution of Pathogenic Yersinia, Some Lights in the Dark; E. Carniel. 2. DNA Adenine Methylation; V.L. Taylor, et al. 3. Tracing Acquisitions and Losses in Yersinia Genomes; A. Rakin, et al. 4. Subtractive Hybridization Uncovers Novel Pathogenicity-Associated Loci in Yersinia enterocolitica; A.N. Iwobi, et al. 5. Identification of Genes Involved in Yersinia pestis Virulence by Signature-Tagged Mutagenesis; Y. Flashner, et al. 6. Characterization of Two Conjugative Yersinia Plasmids Mobilizing pYV; S. Hertwig, et al. 7. Signature-Tagged Mutagenesis of Yersinia pestis; P.C.F. Oyston, et al. 8. Cobalamin Synthesis in Yersinia enterocolitica 8081; M.B. Prentice, et al. 9. Construction of a Yersinia pestis Microarray; R.A. Stabler, et al. 10. A Conjugal Type IV Transfer System in Yersinia enterocolitica Strains; G. Goelz, et al. 11. Transmission Factors: Yersinia pestis Genes Required to Infect the Flea Vector of Plague; B.J. Hinnebusch. Part II: Pathogenesis And Host Interactions. 12. Rho-GTP Binding Proteins in Yersinia Target Cell Interaction; M. Aepfelbacher, et al. 13. A Technique of Intradermal Injection of Yersinia to Study Y. pestis Physiopathology; F. Guinet, E. Carniel. 14. YopT Is A Cysteine Protease Cleaving Rho Family GTPases; Feng Shao, J.E. Dixon. 15. Structural Studies of Yersinia Adhesin YadA; H. Nummelin, et al. 16. Yersinia pseudotuberculosis Harbors a Type IV Pilus Gene Cluster that Contributes to Pathogenicity; F. Collyn, et al. 17. Salicylanilides are Potent Inhibitors of Type III Secretion in Yersinia; A.M. Kauppi, et al. 18. Mapping of Possible Laminin Binding Sites of Y. pestis Plasminogen Activator (Pla) via Phage Display; O. Benedek, et al. 19. The Fish Pathogen Yersinia ruckeri Possesses a TTS System; D.K. Gunasena, et al. 20. Characterisation of the Type III Secretion Protein YscU in Yersinia pseudotuberculosis; M. Lavander, et al. 21. Mutagenesis Elucidates The Assembly Pathway and Structure of Yersinia pestis F1 Polymer; J.E. Kersley, et al. 22. Characterization of Infections with Wild and Mutant Yersinia pseudotuberculosis Strains in Rabbit Oral Model; H. Najdenski, et al. 23. Identification of Yersinia pestis Pigment Receptor; O.N. Podladchikov, G.G. Dikhanov. 24. Yersinia enterocolitica Biotype 1A: Not as Harmless as You Think; S.M. Tennant, et al. 25. Pestoides F, a Yersinia pestis Strain Lacking Plasminogen Activator, is Virulent by the Aerosol Route; P.L. Worsham, C. Roy. 26. Impact of the Yersinia pseudotuberculosis-Derived Mitogen (YPM) on the Murine Immune System; C. Carnoy, et al. 27. Role of T Cells and Gamma Interferon in Yersinia pseudotuberculosis-Derived Mitogen (YPM)-Induced Toxicity in Mice; H. Kano, et al. 28. Yersinia pestis Pla Has Multiple Virulence-Associated Functions; K. Lähteenäki, et al. 29. Polyclonal B-Cell Activation in Mice