The Endometrium

ISBN-13: 9789401178570 / Angielski / Miękka / 2012 / 350 str.

F. a. Kimball

Opis

The Eighth Brook Lodge Conference on Problems of Reproductive Physiology is the latest in a series of small meetings held over 18 years. The topics for trlese meetings have reflected the changing interests and backgrounds of the organizers. The recent rapidly increasing quantity of information on the uterine endometrium and its continuing relevance to fertility control stimulated the organizers to focus the 1979 workshop on this topic. The first four speakers provided a histological background for the molecular and biochemical studies described subsequently. The interaction of biochemist, physiologist, pathologist and physician as they focus their thoughts and talents on this limited area of the body is apparent in the dis- cussions of presentations. This workshop was planned to provide in- sight and a sense of proportion for the participants. For the reader, the record of the proceedings should serve as a useful reference to the state of the art in this area of research. The uterine endometrium is central in the successful implantation and development of the embryo. Examination of the physical relation- ships, biochemical interactions and hormonal influences in this tissue could further advance the understanding of this pivotal tissue in the reproductive process. The depth of the understanding of endo- metrial physiology should be reflected in our ability to better con- trol this reproductive endpoint and to treat its dysfunction. The efforts of many individuals made these Proceedings possible.

Spis treści

I—Endometruul Morphology.- 1. Comparative Morphology of the Endometrium.- 2. Uterine Cell Biology and Phylogenetic Considerations: An Interpretation.- 3. The Endometrium During Implantation.- 4. Endometrial Changes in the Infertile Woman with Particular Reference to Atypism and Its Management.- II—Steroids and the Endometrium.- 5. Estrogen and Progesterone Receptors in Normal and Pathological Human Endometrium.- 6. Characterization of Estrogen Receptors and Biological Responses to Estrogen in Human Endometrium.- 7. Uterine Progesterone Receptors During Pregnancy.- 8. Hormone Production by Rat Blastocysts and Mid-Gestation Trophoblast in Vitro.- 9. Analysis of Hormonal Responses of the Rat Endometrium by the Use of Separated Uterine Cell Types.- 10. Hormonal Regulation of Proliferation and Differentiation of Rabbit Uterine Epithelium: Cell Culture and Animal Studies.- III—Uterine Enzyme Regulation.- 11. Cyclic Change of Estradiol Metabolic Enzymes in Human Endometrium During the Menstrual Cycle.- 12. Mechanisms of Regulation of Uterine Enzyme Levels by Estradiol.- 13. Steroid Regulation of Endometrial Peroxidase.- 14. Reevaluation of Histamine in Implantation.- IV—Prostaglandins and the Uterus.- 15. Endometrial Secretion of Prostaglandins During the Ovarian Cycle and Early Pregnancy.- 16. The Influence of the Embryo on Uterine Prostaglandin Production in the Human.- 17. Prostaglandin I2 and Increased Endometrial Vascular Permeability Preceding the Decidual Cell Reaction.