The Effect of Troleandomycin on Murine Immune Response

ISBN-13: 9783330038011 / Angielski / Miękka / 2017 / 56 str.

Deborah Bush-Munson

Opis

Our research has had a long-standing interest in the effect of antimicrobial antibiotics on the hosts' immune response, and we have found that many drugs from classes such as the macrolides, lincosamides, aminocyclitosis and others have profound effects on the host immune response. Using mouse models we examined drug effect on function of peritoneal-derived phagocytic cells, including neutrophils and macrophages; T cell mediated contact sensitivity; and drug effects on organ clearance of intravenously administered candidal yeasts. Our latest project has involved looking at Troleadomycin, an antibacterial antibiotic made by Pfizer U.S. Pharmaceuticals intended for gram-positive bacterial infections.

O autorze

Deborah Bush-Munson is a tenured Associate Professor and Dental Assisting Program Director at St. Louis Community College. She earned a bachelor and master degree in biology from Southern Illinois University at Edwardsville. Deborah is co-author of scientific journal articles. Currently, she is a doctoral student at Saint Louis University.