The Ebmt Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies

ISBN-13: 9783030022778 / Angielski / Twarda / 2019 / 702 str.

Carreras, Enric

Opis

This Open Access 7 th edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field.Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies.This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills.

Spis treści

Part I. 

Chapter. 1 HSCT: Historical perspective

Storb, R

Chapter. 2 The EBMT: History, present & future

Apperley, J;  Gratwohl, A; Mohty, M

Chapter. 3 The donor registries (organization, regulation, international search...)

Madrigal, A; Evseeva, Irina

Chapter. 4 The HSCT Unit (minimal requirements, data manager trasplant coordinator)

Aljurf, M; Niederwieser, Dietger; Rasheed, Walid

Chapter. 5 JACIE accreditation of HSCT programs

Saccardi, R

Chapter. 6

Statistics in HSCT and Cellular Therapies

Labopin, M; Iacobelli, S; de Wreede, Liesbeth; Szydlo, Richard

Part II. 

Chapter. 7 Biological properties of HSC: scientific basis for HSCT

Chabannon, C ; Aiuti, M

Chapter. 8 Biological properties of cells other than HSC (adaptative, abT, Treg, DC. Innete gdT, IELs MSC, NK)

Toubert, A; Koehl, U; Bondanza, A

Chapter. 9 Histocompatibility (main concepts on HLA)

K. Fleischhauer; Spierings

Chapter. 10 Clinical & biological concepts for mastering Immune reconstitution after HSCT

Boelens, J; Kuball, J

Part III. 

Chapter. 11 Evaluation and counselling of candidates

Rambaldi, A

Chapter. 12 Donor selection  for adults and pediatrics

Ayuk, F; Balduzzi, A

Chapter. 13 Conditioning (MAC, RIC, NMA; including TBI)

Nagler, A

Chapter. 14 Bone marrow harvest

Gorin, Claude

Chapter. 15 Mobilization and collection of HSC

Hübel, K

Chapter. 16 Collection of HSC in children

Peters, C; Witt, Volker

Chapter. 17 Processing, cryopreserving, and controlling the quality of HSC

Wuchter, Patrick

Chapter. 18 Procurement and management of cord blood

Rocha, V; Querol, S

Chapter. 19 Graft manipulation

Handgretinger, R

Chapter. 20 Documentation of engraftment and chimerism after HSCT

Bader, P

Chapter. 21 Short and long term controls after HSCT

Shimoni, A

Part IV. 

Chapter. 22 Vascular access

Cesaro, S

Chapter. 23 Transfusion support

Schrezenmeier, H

Chapter. 24 Fluid and electrolyte management

Masszi, T; Baumgartner, Annic

Chapter. 25 GVHD prophylaxis (immunosuppression)

Socié, G

Chapter. 26 Management ATG (SIRS)

F. Bonifazi

Chapter. 27 Infections control and isolation procedures

Mikulska, M  

Chapter. 28 Pain management

Ahmedzai, SH

Chapter. 29 Specific aspects of management in children

Castagnola, Elio; Riccardi, F

Chapter. 30 Vaccinations

de la Cámara, Rafa

Chapter. 31 Psychological support

Moreno, E ; Schulz-Kindermann, F ; Polomeni, Alice

Chapter. 32 Relevant pharmacological interaction

Bauters, T

Chapter. 33 Role of nursing in HSCT

Babic, A; Murray, J

Chapter. 34 Ethical issues in HSCT

Dalle, JH; El-Ghariani, K

Part V. 

Chapter. 35 Quality assessment of life after HSCT for pediatric and adults

Barata, Anna; Jim, Heather

Chapter. 36 Neutropenic fever

Mikulska, M  

Chapter. 37 Bacterial infections

Averbuch, D

Chapter. 38 Invasive fungal infections

Maertens, J

Chapter. 39 Viral infections (CMC, EVB, VZV, HSV, HHV6, Resp. V, HCV, HBV…) & anti-viral cell therapy

Ljungman, P; Styczynski, J; Einsele, Hermann

Chapter. 40 Other infections in HSCT (Tuberc, Toxo, PCJ, Noc, List.)

Martino, R

Chapter. 41 Bleeding and thrombotic complications

Savani, B

Chapter. 42 Graft failure

Valcárcel , D; Sureda, A

Chapter. 43 Early complications of endothelial origin

Carreras, E

Chapter. 44 Acute GvHD

Greinix, H; Holler, E; Zeiser, R

Chapter. 45 Chronic GvHD

Wolff, D; Lawitschka, A

Chapter. 46 Post-transplant lymphoproliferative syndromes

Styczynski, J ; Giebel, S

Chapter. 47 Iron overload

Angelucci, E

Chapter. 48 Secondary neoplasia (other than PTLPS)

Tichelli, A

Part VI. 

Chapter. 49 Specific organ complications: Ocular / oral / pulmonary / hepatic

Ruutu, T; Hashmi, S

Chapter. 50 Gastrointestinal complications

Basak, G

Chapter. 51 Hemorrhagic cystitis and renal dysfunction

Cesaro, S

Chapter. 52 Pulmonary complications

Carreras, E

Chapter. 53 Neurological complications

Duléry, R

Chapter. 54 Specific organ complications: Skin, hair, musculoskeletal

Ayuk, F; Savani, B

Chapter. 55 Cardiovascular diseases and metabolic syndrome

Snowden, J; Greenfield, D

Chapter.  56 Endocrine, fertility and sexual health

Salooja, N; Shoham,  Z; Balduzzi, A

Part VII. 

Chapter. 57 Monitoring MRD in ALL

Bader, P; Ossenkoppele, G

Chapter. 58 Preventing/treating relapse with drugs

Kröger, N; Mohty, M

Chapter. 59 Preventing relapse by mean cells (DLI, aBT, subsets, tumour specific T cells)

 Kuball, J; Falkenburg, JH Fred; Kolb, HJ; Locatelli, F

Chapter. 60 Cellular therapy (CAR T, TCR T, suicide genes) with management and side effects

Bonini, C; Hudecek, Michael; Fehse, Boris; Bondanza, A

Chapter. 61 Mechanisms of Immune resistance and overcoming immune resistance (checkpoint…)

Dazzi, F; Vago, L

Chapter. 62 Regulatory Aspects of ATMP versus minimally manipulated immune cellsMc Grath, E; Chabannon, C 

Part VIII. 

Chapter. 63 At-home HSCT

Fernández-Avilés, F

Chapter. 64 Cord blood HSCT (adults & children)

Veys, P; Rocha, V; Sanz, J

Chapter. 65 Haploidentical HSCT (TCD and TC-repleted)

Ciceri, F ; Bacigalupo, A

Chapter. 66 Photopheresis in adults and pediatrics

Greinix, H; Gennery, A

Chapter. 67 Pediatric aspects of haploidentical HSCT

Gennery, A; Bertaina, A; Slatter, M; Lankester, A; Albert, M

Chapter. 68 Overweight and obese patients

Langebrake, C 

Chapter. 69 HSCT in Elderly patiens

Duarte, R

Part IX. 

Chapter. 70 EBMT indication for allo and auto HSCT

BOARD

Chapter. 71 AML in adults (incl APL)

Nagler, A; Cornelissen, J; Craddock, C; Sanz, MA

Chapter. 72 AML in children

Gibson, B ; Sauer, M

Chapter.  73 ALL in adults

Marks, D ; Stelljes, M

Chapter. 74 ALL in children and adolescents

Peters, C; Locatelli, F; Bader, P

Chapter. 75 Myelodysplastic syndromes

de Witte, T; Robin, M

Chapter. 76 Refractory Anemia and JMML in children

Niemeyer, CM

Chapter. 77 Myelodysplastic/myeloproliferative syndromes

Onida, F; Chalandon, Y 

Chapter. 78 Myeloproliferative neoplasms (CML, PM, other MPN)

Olavarria E; Kröger, N

Chapter. 79 Severe aplastic anemia and PNH

Dufour C; Peffault de la Tour,  R; Risitano, Antonio Maria

Chapter. 80 Fanconi anemia and other hereditary BMF syndromes

Fioredda, F; Strahm, B; Diaz de Heredia, Cristina; Dalle, JH; Bierings, Marc

Chapter. 81 Hemoglobinopathies (SCA)

Gluckman, E; Abboud, Miguel

Chapter. 82 Multiple myeloma

Mohty, M; Blade, Joan; Bruno, B

Chapter.  83 Systemic light chain amyloidosis

Schönland, S; Minnema, M

Chapter. 84 POEMS syndrome and disease produced by other monoclonal Igs

Cook, G; Rovira, M

Chapter. 85 Low grade NHL (follicular, MALT, MW)

Robinson, S; Kyriacou, C

Chapter. 86 Chronic lymphoid leukemia

Dreger, P; Schetelig, Johannes

Chapter. 87 Diffuse large B cell NHL

Bazarbachi, A; Schmitz, N

Chapter. 88 Mantle cell lymphoma

Dietrich, S; Hermine, O

Chapter. 89 Other T- and B-aggressive lymphomas (Burkitt, LL, PTCL) & Lymphomas associated to HIVHübel, K; Montoto, S

Chapter. 90 Hodgkin lymphoma

Sureda, A; Martinez, Carmen

Chapter. 91 Primary immunodeficiency diseases

Lankester, A; Gennery, A; Albert, M

Chapter. 92 Inborn error of metabolism and osteopetrosis

Schulz, A; Wynn, R

Chapter.93 Autoimmune disease

Snowden, J; Rovira, M; Alexander, T ; Sharrack, B ; Farge, D

Chapter.94 Solid tumors (adults and children)

Lanza, F; Ladenstein, R

Appendix

EBMT Registry

Ruiz, C; Hewer

O autorze

Enric Carreras, MD, PhD, the handbook Project Leader is Director of the Spanish Bone Marrow Donor Registry, Josep Carreras Foundation and Leukemia Research Institute  in Barcelona, Spain

Carlo Dufour, MD, PhD, is Chairperson SAAWP Education Representative at Scientific Council Education, Director Hematology Unit, ay IRCCS Giannina Gaslini, Genoa, Italy

Nicolaus Kröger MD, PhD, is the current EBMT President,  Scientific Council Chair, Professor of Medicine and Medical Director of the Department of Stem Cell Transplantation at the University Medical Center, Hamburg - Eppendorf, Germany

 

Mohamad Mohty, MD, PhD , is past-president of the EBMT, Chairperson ALWP, Professor of  Hematology  and  Head  of  the  Hematology  and  cellular therapy  Department  at  the  Saint-Antoine  Hospital  and  University  Pierre  &  Marie  Curie, Paris, France