The Developing Microbiome: Lessons from Early Life

ISBN-13: 9780128206027 / Angielski / Miękka / 2020 / 308 str.

Erika Chiong Claud

Recenzje

"The microbiome is a living, dynamic environment that develops over time. Infancy is considered the microbiome establishment window that most dramatically impacts neonatal health and long-term adult outcomes. "The Developing Microbiome: Lessons from Early Life” offers a comprehensive view of the status of the pediatric microbiome research space, beginning with the debate surrounding an in utero microbiome and the environmental influences on microbiome succession of the infant and immune development. Succeeding chapters explore the microbiome's role in several specific conditions, including prematurity, intestinal bowel disease, neurodevelopment, food allergy, and obesity or malnutrition. In addition, each chapter includes a section on relevance beyond the pediatric population and the status of microbiome-based therapeutics." --Ann Allergy Asthma Immunol

"This book gives a wonderful review of the research in this quickly evolving and very promising field. The writing is concise and well researched. I doubt it will be a bestseller, but it should be required reading for all pediatric and gastrointestinal residents as well as many others in clinical medicine." --Doody

Spis treści

1. Prenatal - placental microbiome
2. Microbiome establishment and maturation
3. Microbiome and Immune System Development
4. Preterm infant microbiome
5. Preterm infant microbiome and NEC
6. Pediatric microbiome and IBD
7. Microbiome and Neurodevelopment
8. Microbiome and Autism
9. Airway microbiome and asthma
10. Microbiome and food allergy
11. Skin microbiome
12. Microbiome and pediatric Obesity/malnutrition/nutrition
13. Manipulating the microbiome - Probiotics, FMT, Ecotherapeutics

O autorze

Erika Claud, MD specializes in neonatology, providing care to critically ill infants. She has an interest in the diagnosis and treatment of preterm infants and conditions of the immature digestive tract. Dr. Claud's research focuses on the role of the intestinal microbiome in preterm infant development and neonatal necrotizing enterocolitis (NEC) as well as on intestinal epithelial biology as it relates to neonatal necrotizing enterocolitis (NEC), a life-threatening inflammatory bowel disorder of unknown cause that afflicts premature infants. Her work has been funded by grants from prominent institutions, including the March of Dimes and the National Institutes of Health (NIH). A dedicated educator and author, Dr. Claud has published several articles and abstracts in peer-reviewed journals and has written chapters in leading textbooks on pediatric gastrointestinal disease. In addition, she serves as an ad hoc reviewer for several scientific journals, such as the Journal of Pediatrics and Gastroenterology.