The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs

ISBN-13: 9780367447816 / Angielski / Miękka / 2020 / 400 str.

Hans C. Korting; M. Schafer-Korting

Opis

This handbook provides the reader with a more comprehensive look at various facets of benefit-to-risk ratio assessment. It also provides the clinician with data allowing optimization of his decisions on drug treatment.

Spis treści

The Role and Analysis of Benefit and Risk in the Development of New Drugs. Prediction of the Benefit/Risk Ratio from In Vitro Data. Evaluation of Therapeutic Benefits and Toxicological Risks Using Structure-Activity Relational Expert Systems. Improving the Therapeutic Index Through Unusual Routes of Application: Intra-Arterial Treatment of Liver Metastases. Establishing the Benefit/Risk Ration with Combination Drugs. Improving the Therapeutic Index of Antineoplastic Agents through Additional Drugs. Antihypertensive Agents. Diueretics. Anti-Diabetic Drugs. Anticonvulsant Drugs and Drugs for Parkinson's Disease. Antihistamines and Antiserotonins. Cytokines and Immunomodulators. Non-Opioid Analgesics and Anti-Inflammatory Agents. Toxicity Profile of Liposomal Anthacyclines. Antibacterial Agents. Antiviral Agents. Drugs Used in Reproductive Endocrinology. Nicotine Preparations in Smoking. Systemic Drugs for Skin Diseases. Topical Liposome Drugs. Topical Glucocorticoids. Index.

O autorze

Korting, Hans C. | Schafer-Korting, M.